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二甲基亚砜在实验室中的安全使用。

The safe use of dimethyl sulfoxide in the laboratory.

作者信息

Cotter D A

出版信息

Am J Med Technol. 1975 May;41(5):197-8.

PMID:1130429
Abstract

Dimethyl sulfoxide is being increasingly utilized in medical laboratories and in experimental clinical situations. The drug must be considered dangerous since there has been one reported case of fatal allergic reaction and numerous reports of liver damage following exposure to dimethyl sulfoxide. Caution must be exercised in the handling of the drug as it can aid the entry of other drugs into the human body. Although dimethyl sulfoxide is not highly flammable, normal safety precautions used with any flammable solvent are the minimal requirements for safe use of this drug.

摘要

二甲基亚砜在医学实验室和临床实验环境中的应用越来越广泛。鉴于已有一例致命过敏反应的报告以及大量接触二甲基亚砜后肝脏受损的报告,必须将该药物视为危险药物。在处理该药物时必须格外小心,因为它会促进其他药物进入人体。尽管二甲基亚砜的可燃性不高,但对任何易燃溶剂所采用的常规安全预防措施是安全使用该药物的最低要求。

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