Baglin T P
Haematology Department, Addenbrooke's NHS Trust, Cambridge CB2 2QQ, UK.
J Clin Pathol. 2001 Apr;54(4):272-4. doi: 10.1136/jcp.54.4.272.
Heparin induced thrombocytopenia thrombosis (HIT/T) is associated with a high morbidity and mortality. Diagnosis is essentially clinical and negative results of laboratory assays do not exclude the diagnosis. Treatment involves stopping all heparin immediately and giving an alternative thrombin inhibitor. The adoption of low molecular weight heparins is one reason for the reduced incidence of this disease in recent years.
肝素诱导的血小板减少症血栓形成(HIT/T)与高发病率和死亡率相关。诊断主要基于临床,实验室检测结果为阴性并不能排除诊断。治疗包括立即停用所有肝素,并给予替代的凝血酶抑制剂。近年来,低分子量肝素的应用是该疾病发病率降低的一个原因。