转移性胎盘部位滋养细胞肿瘤。1例化疗后完全缓解的病例报告。
Metastatic placental site trophoblastic tumor. Report of a case with complete response to chemotherapy.
作者信息
Mangili G, Garavaglia E, De Marzi P, Zanetto F, Taccagni G
机构信息
Department of Obstetrics and Gynecology, Ospedale San Raffaele, Via Olgettina 60, 20100 Milan, Italy.
出版信息
J Reprod Med. 2001 Mar;46(3):259-62.
BACKGROUND
Placental site trophoblastic tumor (PSTT) is a rare form of gestational trophoblastic neoplasia, commonly insensitive to chemotherapeutic agents.
CASE
We report on long-term remission in a patient with metastatic PSTT after etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine combination chemotherapy. The 27-year-old patient with metastatic lung PSTT was alive, without evidence of disease, > 40 months after treatment.
CONCLUSION
Treatment with multiagent chemotherapy can produce long-term remission, even in patients with metastatic PSTT.
背景
胎盘部位滋养细胞肿瘤（PSTT）是妊娠滋养细胞肿瘤的一种罕见形式，通常对化疗药物不敏感。
病例
我们报告了一名转移性PSTT患者在接受依托泊苷、甲氨蝶呤、放线菌素D、环磷酰胺和长春新碱联合化疗后长期缓解的情况。该27岁转移性肺PSTT患者在治疗后40多个月仍存活，无疾病证据。
结论
即使是转移性PSTT患者，多药联合化疗也可产生长期缓解。
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