牛脱矿骨基质对兔颅骨骨修复过程的组织学研究。

Histologic study of a bovine demineralized bone matrix on bone repair process in rabbits calvaria.

作者信息

Garcia R R, Barbosa J R

机构信息

Department of Oral Maxillofacial Surgery, Dental School, UniCamp, Piracicaba, Brazil.

出版信息

Indian J Dent Res. 2000 Oct-Dec;11(4):131-8.

PMID:11307636

Abstract

The aim of this study was to evaluate histologically the bovine demineralized bone matrix, Osseobond, on bone repair process in rabbit's calvaria. Nine rabbits were used and two surgical defects were created on each calvaria, one was just filled with the animal blood and the other was filled with demineralized bone matrix. The animals were sacrificed in postoperative period of 3, 7, and 15 weeks. Specimens on light microscopy analysis revealed that bone repair were improved on cavities filled with bovine demineralized bone matrix.

摘要

本研究的目的是通过组织学方法评估牛脱矿骨基质Osseobond对兔颅骨骨修复过程的影响。使用了9只兔子，在每只颅骨上制造两个手术缺损，一个仅填充动物血液，另一个填充脱矿骨基质。在术后3周、7周和15周处死动物。光学显微镜分析标本显示，填充牛脱矿骨基质的空洞处骨修复得到改善。