McGovern M C, Carson D
The Royal Belfast Hospital for Sick Children, Northern Ireland.
Ir Med J. 2001 Feb;94(2):38, 40.
To ascertain if significant hypoglycaemic episodes can be avoided or managed more appropriately in children with insulin dependent diabetes mellitus (IDDM). A retrospective chart audit was performed on all children with IDDM admitted with hypoglycaemia between 1.1.90 and 31.8.97. Of the 21 children studied, 9 presented with seizures and 1 with coma. In 9 the hypoglycaemia was unexplained. Only 6 parents used glucagon. Five children were readmitted during the review with a further hypoglycaemic episode. Four of these had their first admission significantly sooner after diagnosis than those without recurrent episodes. Hypoglycaemic episodes are often unexplained and are unlikely to be completely avoidable. Improved support services during intercurrent illness may reduce the frequency of some hypoglycaemic episodes and increased use of glucagon at home may reduce the severity of some. Children who have their first hypoglycaemic episode within one year of diagnosis are at risk of having recurrent episodes.
为确定在胰岛素依赖型糖尿病(IDDM)患儿中是否能够避免严重低血糖发作或对其进行更恰当的处理。对1990年1月1日至1997年8月31日期间因低血糖入院的所有IDDM患儿进行了回顾性病历审查。在研究的21名儿童中,9名出现惊厥,1名出现昏迷。9例低血糖原因不明。只有6名家长使用了胰高血糖素。在审查期间,5名儿童因再次出现低血糖发作而再次入院。其中4名患儿首次入院时间比未复发的患儿在诊断后明显更早。低血糖发作常常原因不明,且不太可能完全避免。在并发疾病期间改善支持服务可能会减少某些低血糖发作的频率,在家中增加胰高血糖素的使用可能会减轻某些发作的严重程度。在诊断后一年内首次发生低血糖发作的儿童有复发的风险。