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[斯威特综合征]

[Sweet's syndrome].

作者信息

Chakroun M, Ben Romdhane F, Mohamed W B, Loussaief C, Amri M, Zakhama A, Zili J, Bouzouaia N

机构信息

Service des Maladies Infectieuses, CHU Monastir.

出版信息

Tunis Med. 2001 Jan;79(1):42-6.

Abstract

Sweet's syndrome or acute febrile neutrophilic dermatosis is relatively frequent. It can be isolated or associated to other diseases, particularly, inflammatory or autoimmune diseases, lymphoproliferative or malignant disorders. In this retrospective study, we report 10 cases of Sweet's syndrome recorded over a 42 months period. The female predominance was net (9 womens for 1 man). The mean age was 45 years. The diagnosis was established, in all cases, on clinical, biological and histological criteria. The lesions occurred most commonly on legs (9 cases). The failure of antibiotics has been noted in all patients, and colchicine has been demonstrated efficient in 6 patients. Our study confirms the interest of cutaneous biopsy in case of papulo-nodular lesions which has not respond to antibiotics.

摘要

斯威特综合征或急性发热性嗜中性皮病相对常见。它可以单独出现,也可与其他疾病相关,特别是炎症性或自身免疫性疾病、淋巴增殖性或恶性疾病。在这项回顾性研究中,我们报告了在42个月期间记录的10例斯威特综合征病例。女性占绝对优势(9名女性对1名男性)。平均年龄为45岁。所有病例均根据临床、生物学和组织学标准确诊。病变最常发生在腿部(9例)。所有患者均对抗生素治疗无效,秋水仙碱在6例患者中显示有效。我们的研究证实了对于对抗生素无反应的丘疹结节性病变进行皮肤活检的意义。

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