Tai L H, Johnston J O, Klein H Z, Rowland J, Sudilovsky D
Department of Pathology, University of California at San Francisco, San Francisco, California, USA.
Diagn Cytopathol. 2001 May;24(5):336-9. doi: 10.1002/dc.1072.
Calcifying aponeurotic fibroma is a rare benign soft tissue proliferation, which occurs in the distal extremities in children. We describe a case of calcifying aponeurotic fibroma of the hand in a 9 year-old male diagnosed by FNA. Clinically and radiographically this mass was felt to be suspicious for sarcoma, likely alveolar rhabdomyosarcoma. Cytologic examination revealed benign appearing spindled cells, chondroid cells, multinucleated giant cells and calcific debris. These features recapitulate the classic histologic features of calcifying aponeurotic fibroma. Conservative excision was performed and histologic exam confirmed the diagnosis. To the authors' knowledge, this is the first description of the cytologic features of this entity.
钙化性腱膜纤维瘤是一种罕见的良性软组织增生,发生于儿童的四肢远端。我们描述了一例9岁男性手部钙化性腱膜纤维瘤病例,通过细针穿刺抽吸活检(FNA)确诊。临床和影像学检查认为该肿块疑似肉瘤,可能为肺泡状横纹肌肉瘤。细胞学检查显示出良性的梭形细胞、软骨样细胞、多核巨细胞和钙化碎片。这些特征重现了钙化性腱膜纤维瘤的经典组织学特征。进行了保守性切除,组织学检查证实了诊断。据作者所知,这是对该实体细胞学特征的首次描述。