Janssen A G, Mansour K, Bos J J, Castelijns J A
Department of Diagnostic and Interventional Radiology, De Tjongerschans Hospital, Thialfweg 44, 8441 PW Heerenveen, the Netherlands.
AJNR Am J Neuroradiol. 2001 May;22(5):845-50.
Epiphora, or tearing due to primary acquired nasolacrimal duct obstruction (PANDO), is increasingly being treated with balloon dilatation. The cause of PANDO is unknown, but a small diameter of the bony nasolacrimal canal might be one of the etiologic factors. The purpose of this study was to determine the normal distribution of diameters of the bony canal and to ascertain whether there is an association between the diameter of the bony canal and primary nasolacrimal duct obstruction.
Using axial CT, we measured the minimum diameter of the bony nasolacrimal canal in a control group of 50 men and 50 women and in 19 patients with PANDO.
The mean minimum diameter in the control group was 3.5 mm, which was smaller than expected on the basis of published data. The difference between the mean minimum diameter in men (3.70 mm) and that in women (3.35 mm) was significant. The mean minimum diameter in the patient group was 3.0 mm, which was significantly smaller than that in the control group. There was, however, considerable overlap.
A small diameter of the bony canal appears to be one of the etiologic factors in PANDO.
由于原发性获得性鼻泪管阻塞（PANDO）导致的溢泪或流泪，越来越多地采用球囊扩张术进行治疗。PANDO的病因尚不清楚，但骨性鼻泪管直径较小可能是病因之一。本研究的目的是确定骨性鼻泪管直径的正常分布，并确定骨性鼻泪管直径与原发性鼻泪管阻塞之间是否存在关联。
我们使用轴向CT测量了50名男性和50名女性对照组以及19例PANDO患者的骨性鼻泪管最小直径。
对照组的平均最小直径为3.5mm，比已发表数据预期的要小。男性（3.70mm）和女性（3.35mm）的平均最小直径差异显著。患者组的平均最小直径为3.0mm，明显小于对照组。然而，两组之间存在相当大的重叠。
骨性鼻泪管直径较小似乎是PANDO的病因之一。
