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凝血酶注射治疗股动脉假性动脉瘤并发血栓栓塞:动脉内溶栓治疗

Thromboembolism complicating thrombin injection of femoral artery pseudoaneurysm: management with intraarterial thrombolysis.

作者信息

Sadiq S, Ibrahim W

机构信息

Department of Radiology, St. Joseph Mercy Hospital, 44405 Woodward Ave., Pontiac, Michigan 48341, USA.

出版信息

J Vasc Interv Radiol. 2001 May;12(5):633-6. doi: 10.1016/s1051-0443(07)61490-0.

Abstract

Ultrasound (US)-guided compression of pseudoaneurysms is being rapidly replaced by US-guided percutaneous treatment with thrombin injection because of the less intensive nature of this procedure. Thromboembolism after percutaneous treatment with thrombin injection is rare and has been described in brachial artery pseudoaneurysms. These were managed with intravenous administration of heparin and surgical thrombectomy. In this report, the authors describe thromboembolic complication of thrombin injection after treatment of a femoral artery pseudoaneurysm. This was managed by intraarterial thrombolysis with use of recombinant tissue plasminogen activator (rt-PA) with resolution of all major occlusive changes. A lower dose of thrombin injection and frequent postprocedural monitoring of distal pulses is recommended.

摘要

由于超声(US)引导下经皮注射凝血酶治疗假性动脉瘤的操作强度较低,超声引导下压迫假性动脉瘤的方法正迅速被其取代。经皮注射凝血酶治疗后的血栓栓塞很少见,且仅在肱动脉假性动脉瘤中有相关报道。这些病例通过静脉注射肝素和外科血栓切除术进行处理。在本报告中,作者描述了一例股动脉假性动脉瘤治疗后经皮注射凝血酶引发的血栓栓塞并发症。该并发症通过动脉内使用重组组织型纤溶酶原激活剂(rt-PA)进行溶栓治疗,所有主要闭塞性改变均得到缓解。建议采用较低剂量的凝血酶注射,并在术后频繁监测远端脉搏。

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