Ratner P A, Bottorff J L, Johnson J L, Cook R, Lovato C Y
School of Nursing, University of British of Columbia, Vancouver, Canada.
Cancer Detect Prev. 2001;25(2):147-60.
The purpose of this study was to identify factors that influence the effectiveness of interventions in increasing women's use of mammography screening programs. To this end, we conducted a systematic literature review of studies published between 1966 and 1997. In this review, we recorded data about the year and country in which studies were completed, the study design, the methods for measuring screening rates, various sample characteristics, the nature of the intervention, and the resulting screening rates. The PRECEDE model was used as a framework to make distinctions between the various interventions. To synthesize evidence about the baseline screening rates and the effect of interventions on the incidence of mammography screening, we fit random-effects logistic regression models. These models revealed that more recent studies (those conducted from 1990 to 1996) were associated with higher screening rates (odds ratio [OR], 2.1; 95% confidence interval [CI], 1.2-3.9). Conversely, those designed to target older women (minimum age, 50-65 years) and those set in clinics exhibited smaller screening rates (OR, 0.6, 95% CI, 0.3-1.0, and OR, 0.5; 95% CI, 0.3-0.8, respectively). The meta-analyses also suggested methodologic issues that must be considered before the relative strength of various interventions can be assessed rigorously.
本研究的目的是确定影响干预措施提高女性乳腺钼靶筛查项目使用率有效性的因素。为此,我们对1966年至1997年间发表的研究进行了系统的文献综述。在该综述中,我们记录了研究完成的年份和国家、研究设计、测量筛查率的方法、各种样本特征、干预措施的性质以及由此产生的筛查率。PRECEDE模型被用作区分各种干预措施的框架。为了综合关于基线筛查率以及干预措施对乳腺钼靶筛查发生率影响的证据,我们拟合了随机效应逻辑回归模型。这些模型显示,较新的研究(1990年至1996年进行的研究)与较高的筛查率相关(优势比[OR],2.1;95%置信区间[CI],1.2 - 3.9)。相反,针对老年女性(最低年龄50 - 65岁)设计的研究以及在诊所开展的研究显示出较低的筛查率(OR分别为0.6,95% CI,0.3 - 1.0;以及OR,0.5;95% CI,0.3 - 0.8)。荟萃分析还提出了在严格评估各种干预措施的相对强度之前必须考虑的方法学问题。