睡眠期间经皮电刺激对阻塞性睡眠呼吸暂停的影响

[The effects of transcutaneous electrical stimulation during sleep on obstructive sleep apnea].

作者信息

Piao S, He Y, Yuan F

机构信息

322th Hospital of PLA, Datong 037006.

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 1998 Aug;21(8):492-3.

PMID:11360522

Abstract

OBJECTIVE

To study the effects of transcutaneous electrical stimulation during sleep on obstructive sleep apnea syndrom (OSAS).

METHOD

Sixteen patients with OSAS were studied by polysomnography during all-night sleep with and without submental transcutaneous electrical stimulation (TES) of the genioglossus.

RESULT

Fourteen of the 16 patients (87%) who accepted the TES were treated successfully (reduction of Al > 50%). The average apnea index showed a decrease of 29 events per hour when the TES were performed (P < 0.001). The average apnea time decreased from 22 to 7 sec (P < 0.001). The apnea time/TST decreased from 27% +/- 11% to 7% +/- 3%. The lowest SaO2 increased from 71% to 87% (P < 0.001). TES did not cause arousal. The sleep stages of SWS, and REM sleep effect (SE) increased significantly.

CONCLUSION

TES is a conservative but effective treatment in patients with obstructive sleep apnea syndrome, although it failed to improve central sleep apnea.

摘要

目的

研究睡眠期间经皮电刺激对阻塞性睡眠呼吸暂停综合征（OSAS）的影响。

方法

对16例OSAS患者在全夜睡眠期间进行多导睡眠图监测，监测期间分别给予和不给予颏下经皮舌肌电刺激（TES）。

结果

16例接受TES治疗的患者中有14例（87%）治疗成功（呼吸暂停低通气指数降低>50%）。进行TES时，平均呼吸暂停指数每小时减少29次事件（P<0.001）。平均呼吸暂停时间从22秒降至7秒（P<0.001）。呼吸暂停时间/总睡眠时间从27%±11%降至7%±3%。最低血氧饱和度从71%升至87%（P<0.001）。TES未引起觉醒。慢波睡眠和快速眼动睡眠效应（SE）的睡眠阶段显著增加。