[细胞性血管纤维瘤。一种罕见的外阴肿瘤。病例报告]

[Cellular angiofibroma. A rare vulvar tumor. Report of a case].

作者信息

Colombat M, Liard-Meillon M E, De Saint-Maur P, Sevestre H, Gontier M F

机构信息

Service d'Anatomie et Cytologie Pathologiques, CHU, 1 place Victor Pauchet, 80054 Amiens cedex 1, France.

出版信息

Ann Pathol. 2001 Apr;21(2):145-8.

PMID:11373584

Abstract

Cellular angiofibroma is a rare tumor. We report a vulvar case in a 37 year old woman. This nodular, well circonscribed tumor consists of bland spindle cells, numerous thin or thick often hyalinized vessels and adipocytes. The stromal cells are positive for vimentin and negative for CD34, protein S100, smooth muscle actin, desmin, epithelial membrane antigen and cytokeratin. Cellular angiofibroma is a benign tumor that has to be differentiated from aggressive angiomyxoma, angiomyofibroblastoma, glomangiopericytoma, spindle cell lipoma, solitary fibrous tumor and perineurioma.

摘要

细胞性血管纤维瘤是一种罕见肿瘤。我们报告一例发生于一名37岁女性外阴的病例。这个结节状、边界清楚的肿瘤由温和的梭形细胞、许多薄的或厚的且常呈玻璃样变的血管以及脂肪细胞组成。间质细胞波形蛋白阳性，而CD34、蛋白S100、平滑肌肌动蛋白、结蛋白、上皮膜抗原和细胞角蛋白阴性。细胞性血管纤维瘤是一种良性肿瘤，必须与侵袭性血管黏液瘤、血管肌纤维母细胞瘤、肾小球血管外皮细胞瘤、梭形细胞脂肪瘤、孤立性纤维性肿瘤和神经束膜瘤相鉴别。