缩乳术可改善巨乳症患者的保乳治疗效果。
Reduction mammoplasty improves breast conservation therapy in patients with macromastia.
作者信息
Newman L A, Kuerer H M, McNeese M D, Hunt K K, Gurtner G C, Vlastos G S, Robb G, Singletary S E
机构信息
Department of Surgical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
出版信息
Am J Surg. 2001 Mar;181(3):215-20. doi: 10.1016/s0002-9610(01)00563-3.
BACKGROUND
Macromastia has been considered a contraindication to breast conservation therapy because of difficulties with radiation therapy. This study evaluates the feasibility of bilateral reduction mammoplasty as a component of breast conservation therapy for breast cancer patients with pendulous breasts.
METHODS
Of 153 patients undergoing reduction mammoplasty at the University of Texas M. D. Anderson Cancer Center, 28 were identified as breast cancer patients with macromastia receiving breast conservation therapy. Median follow-up was 23.8 months.
RESULTS
Median patient age was 55 years. Nearly all patients were described as obese. Median weight of the reduction mammoplasty specimen on the cancerous side was 766 g. One patient (4%) required completion mastectomy for inadequate margin control. Major postoperative complications occurred in 2 patients (7%). There were no major postradiation complications. Patient survey revealed a satisfaction rate of 86%.
CONCLUSION
Bilateral reduction mammoplasty is a reasonable and safe option for breast cancer patients with macromastia who desire breast conservation therapy.
背景
由于放射治疗存在困难，巨乳症一直被视为保乳治疗的禁忌证。本研究评估双侧乳房缩小成形术作为乳房下垂的乳腺癌患者保乳治疗一部分的可行性。
方法
在德克萨斯大学MD安德森癌症中心接受乳房缩小成形术的153例患者中，28例被确定为患有巨乳症且正在接受保乳治疗的乳腺癌患者。中位随访时间为23.8个月。
结果
患者中位年龄为55岁。几乎所有患者都被描述为肥胖。患侧乳房缩小成形术标本的中位重量为766克。1例患者（4%）因切缘控制不佳需要行乳房全切术。2例患者（7%）发生了严重术后并发症。没有严重的放疗后并发症。患者调查显示满意率为86%。
结论
对于希望接受保乳治疗的巨乳症乳腺癌患者，双侧乳房缩小成形术是一种合理且安全的选择。
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