相似文献
1
The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway.
EMBO J. 2001 Jun 1;20(11):2789-801. doi: 10.1093/emboj/20.11.2789.
2
The transforming growth factor-beta/SMAD signaling pathway is present and functional in human mesangial cells.
Kidney Int. 1999 Oct;56(4):1354-65. doi: 10.1046/j.1523-1755.1999.00680.x.
3
A novel dominant negative Smad2 mutation in a TGFbeta resistant human carcinoma cell line.
Anticancer Res. 2002 Jan-Feb;22(1A):13-9.
4
SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor.
Cell. 1998 Dec 11;95(6):779-91. doi: 10.1016/s0092-8674(00)81701-8.
5
Transcriptional regulation of Smad2 is required for enhancement of TGFbeta/Smad signaling by TGFbeta inducible early gene.
J Cell Biochem. 2002;87(2):233-41. doi: 10.1002/jcb.10299.
6
Selective inhibition of activin receptor-like kinase 5 signaling blocks profibrotic transforming growth factor beta responses in skin fibroblasts.
Arthritis Rheum. 2004 Dec;50(12):4008-21. doi: 10.1002/art.20658.
7
Tumor-derived C-terminal mutations of Smad4 with decreased DNA binding activity and enhanced intramolecular interaction.
Oncogene. 2004 Feb 5;23(5):1021-9. doi: 10.1038/sj.onc.1207219.
8
The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling.
Genes Dev. 1999 Sep 1;13(17):2196-206. doi: 10.1101/gad.13.17.2196.
9
Modulation of the TGFbeta/Smad signaling pathway in mesangial cells by CTGF/CCN2.
Exp Cell Res. 2005 Jul 15;307(2):305-14. doi: 10.1016/j.yexcr.2005.03.022. Epub 2005 Apr 22.
10
Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta.
EMBO J. 2000 Oct 2;19(19):5178-93. doi: 10.1093/emboj/19.19.5178.
引用本文的文献
1
Advances and Challenges in Targeting TGF-β Isoforms for Therapeutic Intervention of Cancer: A Mechanism-Based Perspective.
Pharmaceuticals (Basel). 2024 Apr 20;17(4):533. doi: 10.3390/ph17040533.
2
Disable 2, A Versatile Tissue Matrix Multifunctional Scaffold Protein with Multifaceted Signaling: Unveiling Role in Breast Cancer for Therapeutic Revolution.
Cell Biochem Biophys. 2024 Jun;82(2):501-520. doi: 10.1007/s12013-024-01261-5. Epub 2024 Apr 9.
3
Targeting SMAD-Dependent Signaling: Considerations in Epithelial and Mesenchymal Solid Tumors.
Pharmaceuticals (Basel). 2024 Mar 1;17(3):326. doi: 10.3390/ph17030326.
4
Disabled-2, a versatile tissue matrix multifunctional scaffold protein with multifaceted signaling: Unveiling its potential in the cancer battle.
Naunyn Schmiedebergs Arch Pharmacol. 2024 Aug;397(8):5533-5557. doi: 10.1007/s00210-024-03037-3. Epub 2024 Mar 19.
5
Genome-wide association studies reconstructing chronic kidney disease.
Nephrol Dial Transplant. 2024 Feb 28;39(3):395-402. doi: 10.1093/ndt/gfad209.
6
Disabled-2: a protein up-regulated by high molecular weight hyaluronan has both tumor promoting and tumor suppressor roles in ovarian cancer.
Cell Mol Life Sci. 2023 Oct 10;80(11):320. doi: 10.1007/s00018-023-04972-9.
7
DAB2 promotes pulmonary fibrosis and may act as an intermediate between IGF‑1R and PI3K/AKT signaling pathways.
Exp Ther Med. 2023 Mar 10;25(4):183. doi: 10.3892/etm.2023.11882. eCollection 2023 Apr.
8
Disabled-2 (): A Key Regulator of Anti- and Pro-Tumorigenic Pathways.
Int J Mol Sci. 2022 Dec 31;24(1):696. doi: 10.3390/ijms24010696.
9
Chemotherapy induces feedback up-regulation of CD44v6 in colorectal cancer initiating cells through -catenin/MDR1 signaling to sustain chemoresistance.
Front Oncol. 2022 Oct 18;12:906260. doi: 10.3389/fonc.2022.906260. eCollection 2022.
10
The effect of eight weeks of moderate and high intensity aerobic training on the gene expression of Mir-145, Wnt3a and Dab2 in the heart tissue of type 2 diabetic rats.
J Diabetes Metab Disord. 2021 Oct 16;20(2):1597-1604. doi: 10.1007/s40200-021-00909-w. eCollection 2021 Dec.
本文引用的文献
1
Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2.
Traffic. 2001 Feb;2(2):111-23. doi: 10.1034/j.1600-0854.2001.020206.x.
2
Smad7 is induced by CD40 and protects WEHI 231 B-lymphocytes from transforming growth factor-beta -induced growth inhibition and apoptosis.
J Biol Chem. 2000 Dec 8;275(49):38363-70. doi: 10.1074/jbc.M004861200.
3
The nuclear import function of Smad2 is masked by SARA and unmasked by TGFbeta-dependent phosphorylation.
Nat Cell Biol. 2000 Aug;2(8):559-62. doi: 10.1038/35019649.
4
Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalin.
Biochem J. 2000 May 1;347 Pt 3(Pt 3):613-21.
5
FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors.
Mol Cell Biol. 2000 Feb;20(3):979-89. doi: 10.1128/MCB.20.3.979-989.2000.
6
Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription.
J Biol Chem. 1999 Dec 24;274(52):37413-20. doi: 10.1074/jbc.274.52.37413.
7
Specificity, diversity, and regulation in TGF-beta superfamily signaling.
FASEB J. 1999 Dec;13(15):2105-24.
8
Reelin is a ligand for lipoprotein receptors.
Neuron. 1999 Oct;24(2):471-9. doi: 10.1016/s0896-6273(00)80860-0.
9
The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids.
Mol Cell Biol. 1999 Jul;19(7):5179-88. doi: 10.1128/MCB.19.7.5179.
10
Regulation of Smad signalling by protein associations and signalling crosstalk.
Trends Cell Biol. 1999 Jul;9(7):274-9. doi: 10.1016/s0962-8924(99)01579-2.
Zotero 插件