一名青少年患者中与奥氮平相关的糖尿病酮症酸中毒

Diabetic ketoacidosis associated with olanzapine in an adolescent patient.

作者信息

Selva K A, Scott S M

机构信息

Division of Pediatric Endocrinology, University of New Mexico Children's Hospital, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.

出版信息

J Pediatr. 2001 Jun;138(6):936-8. doi: 10.1067/mpd.2001.114016.

DOI:10.1067/mpd.2001.114016

PMID:11391346

Abstract

Olanzapine (Zyprexa) is an atypical neuroleptic used in adult and pediatric patients for the management of schizophrenia. Common side effects include increased appetite and weight gain. An uncommon but severe adverse effect is the development of diabetic ketoacidosis, reported until now only in adults. We report a case of acute onset diabetic ketoacidosis presenting in a 16-year-old girl during olanzapine therapy.

摘要

奥氮平（再普乐）是一种非典型抗精神病药物，用于成人和儿童患者治疗精神分裂症。常见副作用包括食欲增加和体重增加。一种罕见但严重的不良反应是糖尿病酮症酸中毒的发生，迄今为止仅在成人中报道过。我们报告一例16岁女孩在接受奥氮平治疗期间出现急性糖尿病酮症酸中毒的病例。