Rock W A, Meeks G R
Departments of Pathology and of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, USA.
J Reprod Med. 2001 May;46(5 Suppl):507-14.
Hysterectomy is the second-most-common surgical procedure among premenopausal women. The conditions that lead to the need for a hysterectomy often are accompanied by chronic blood loss that can lead to anemia. Moreover, hysterectomy and myomectomy may result in significant blood loss, which exacerbates the anemia. The presence of fatigue associated with anemia has a substantially negative impact on quality of life and the ability to perform activities of daily living. Options for alleviating perioperative anemia include minimizing surgical blood loss, blood transfusion, supplementation with hematinics, such as iron and folic acid, and treatment with recombinant human erythropoietin. Treating preoperative anemia is expected to help correct anemia prior to surgery and may have a positive impact on anemia-related symptoms and surgical outcomes.
子宫切除术是绝经前女性中第二常见的外科手术。导致需要进行子宫切除术的病症通常伴有慢性失血，进而可能导致贫血。此外，子宫切除术和肌瘤切除术可能会导致大量失血，这会加重贫血。与贫血相关的疲劳会对生活质量和进行日常生活活动的能力产生重大负面影响。缓解围手术期贫血的选择包括尽量减少手术失血、输血、补充造血剂（如铁和叶酸）以及使用重组人促红细胞生成素进行治疗。治疗术前贫血有望在手术前帮助纠正贫血，并可能对贫血相关症状和手术结果产生积极影响。
