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加拿大普通人群中重度抑郁发作的持续时间。

The duration of major depressive episodes in the Canadian general population.

作者信息

Patten S C

机构信息

Department of Community Health Sciences, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada.

出版信息

Chronic Dis Can. 2001;22(1):6-11.

Abstract

The National Population Health Survey (NPHS) has provided a wealth of new data concerning major depression in the Canadian general population. The NPHS included a brief predictor of major depression, and also two questions (only one of which was asked of each subject) concerned with the duration of episodes in the preceding year. A striking finding was that many of the episodes identified were very brief. In this paper the NPHS data were examined from a different perspective in order to derive a complementary perspective on the episode duration data. Data from the 1994/95 and 1996/97 cycles of the NPHS were used in the analysis. The longitudinal data were used to generate approximations of age and gender-specific incidence for members of the population over the age of 12 years. An estimate of prevalence was made from the 1996/97 cross-sectional file. A basic expression relating prevalence to incidence and mean duration of illness was then applied within age and gender categories. Taken together, the incidence and prevalence data from the NPHS suggest a longer duration than was indicated by the NPHS interview duration item. A probable explanation is that the NPHS duration question had an upper limit of 52 weeks, whereas some episodes of major depression last longer than this. Particularly long episodes could have a large impact on mean duration in the population. Nevertheless, these data confirm the heterogenous nature of this condition; many people with the syndrome of major depression may have quite brief episodes.

摘要

全国人口健康调查(NPHS)提供了大量有关加拿大普通人群中重度抑郁症的新数据。NPHS包含了一个重度抑郁症的简短预测指标,还有两个关于前一年发作持续时间的问题(每个受试者仅被问到其中一个问题)。一个惊人的发现是,所识别出的许多发作都非常短暂。在本文中,从不同角度对NPHS数据进行了审视,以便得出关于发作持续时间数据的补充观点。分析中使用了NPHS 1994/95和1996/97周期的数据。纵向数据用于生成12岁以上人群中按年龄和性别划分的发病率近似值。患病率估计值来自1996/97年的横断面档案。然后在年龄和性别类别中应用了一个将患病率与发病率和疾病平均持续时间相关联的基本表达式。综合来看,NPHS的发病率和患病率数据表明发作持续时间比NPHS访谈中关于持续时间的项目所显示的要长。一个可能的解释是,NPHS关于持续时间的问题上限为52周,而一些重度抑郁症发作持续时间超过了这个时长。特别长的发作可能会对总体平均持续时间产生很大影响。尽管如此,这些数据证实了这种病症的异质性;许多患有重度抑郁症综合征的人可能发作相当短暂。

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