Jourdain O, Hopirtean V, Saint-Amand H, Dallay D
Polyclinique Jean-Villar, avenue Maryse-Bastié, 33520 Bordeaux Bruges, Cedex, France.
J Gynecol Obstet Biol Reprod (Paris). 2001 May;30(3):265-71.
To evaluate fertility after laparoscopic treatment of ectopic pregnancy (EP). To investigate factors influencing fertility and EP recurrence.
Retrospective study of a series of 138 patients. Rate of intra uterine pregnancy, live births and recurrent EP were the main outcome measures. Subsequent fertility was assessed by calculating cumulative intrauterine pregnancy rates and were analyzed by log-rank tests and Cox regression.
The multivariate analysis showed a better rate of intra uterine pregnancy in patients with normal controlateral tube and in women younger than 30. The average time before conception was 11.5 months. After 18 months of infertility the intra-uterine pregnancy rate was low but the EP recurrence rate increased after 24 months. In this study there was no difference between radical and conservative surgery treatment.
Laparoscopy is useful in the management of ectopic pregnancy, especially in order to establish a prognosis for fertility.
评估腹腔镜治疗异位妊娠(EP)后的生育能力。研究影响生育能力和EP复发的因素。
对138例患者进行回顾性研究。主要观察指标为宫内妊娠率、活产率和EP复发率。通过计算累积宫内妊娠率评估后续生育能力,并采用对数秩检验和Cox回归分析。
多因素分析显示,对侧输卵管正常的患者和年龄小于30岁的女性宫内妊娠率更高。受孕前的平均时间为11.5个月。不孕18个月后宫内妊娠率较低,但24个月后EP复发率升高。本研究中,根治性手术和保守性手术治疗之间无差异。
腹腔镜检查在异位妊娠的管理中有用,尤其是为了确定生育预后。