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[妇科癌症中的生育力保存]

[Fertility preservation in gynecologic cancer].

作者信息

Tropé C, Scheistrøen M, Makar A P

机构信息

Gynekologisk avdeling Det Norske Radiumhospital 0310 Oslo.

出版信息

Tidsskr Nor Laegeforen. 2001 Apr 20;121(10):1234-9.

Abstract

Recent advances in both the staging and the understanding of the natural history of gynecologic cancers have led to new approaches to treatment. The treatment can now often be tailored to the extent of the disease, and preservation of child-bearing ability and/or sexual function may be possible for certain women with early invasive cancers of the ovary, cervix, endometrium, vagina and vulva. Better understanding of the tumour biology and clinicopathologic factors of prognostic significance will allow for individualization of treatment. Management of patients with early gynecologic cancer should be individualized with the risks of conservative therapy balanced against the dangers and advantages of more radical therapy. Specialists in gynecologic oncology and infertility together with an informed patient and her family should make treatment decisions. In this article we present an overview of the therapeutic management of early invasive cancers of the ovary, cervix and endometrium, and present guidelines that may help preserve childbearing capacity.

摘要

妇科癌症分期及对其自然史理解方面的最新进展,催生了新的治疗方法。现在,治疗通常可根据疾病程度进行调整,对于某些患有早期卵巢、宫颈、子宫内膜、阴道和外阴浸润性癌的女性,保留生育能力和/或性功能成为可能。对具有预后意义的肿瘤生物学和临床病理因素有更深入的了解,将有助于实现治疗的个体化。早期妇科癌症患者的管理应个体化,权衡保守治疗的风险与更激进治疗的危险和益处。妇科肿瘤学和不孕症专家应与了解情况的患者及其家属共同做出治疗决策。在本文中,我们概述了早期卵巢、宫颈和子宫内膜浸润性癌的治疗管理,并提出了可能有助于保留生育能力的指导原则。

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