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Mutation in the U2 snRNA influences exon interactions of U5 snRNA loop 1 during pre-mRNA splicing.
EMBO J. 2006 Aug 23;25(16):3813-22. doi: 10.1038/sj.emboj.7601258. Epub 2006 Aug 3.
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The U1 snRNP protein U1C recognizes the 5' splice site in the absence of base pairing.
Nature. 2002 Sep 5;419(6902):86-90. doi: 10.1038/nature00947.
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Base pairing between U2 and U6 snRNAs is necessary for splicing of a mammalian pre-mRNA.
Nature. 1991 Aug 29;352(6338):818-21. doi: 10.1038/352818a0.

引用本文的文献

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Human spliceosomal snRNA sequence variants generate variant spliceosomes.
RNA. 2021 Oct;27(10):1186-1203. doi: 10.1261/rna.078768.121. Epub 2021 Jul 7.
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A protein map of the yeast activated spliceosome as obtained by electron microscopy.
RNA. 2016 Sep;22(9):1427-40. doi: 10.1261/rna.057778.116. Epub 2016 Jul 1.
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RNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic core.
EMBO J. 2013 Oct 30;32(21):2804-18. doi: 10.1038/emboj.2013.198. Epub 2013 Sep 3.
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Structural analyses of the pre-mRNA splicing machinery.
Protein Sci. 2013 Jun;22(6):677-92. doi: 10.1002/pro.2266. Epub 2013 May 8.
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A unique spatial arrangement of the snRNPs within the native spliceosome emerges from in silico studies.
Structure. 2012 Jun 6;20(6):1097-106. doi: 10.1016/j.str.2012.03.022. Epub 2012 May 10.
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Mutations in the U5 snRNA result in altered splicing of subsets of pre-mRNAs and reduced stability of Prp8.
RNA. 2009 Jul;15(7):1292-304. doi: 10.1261/rna.1347409. Epub 2009 May 15.
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The U1, U2 and U5 snRNAs crosslink to the 5' exon during yeast pre-mRNA splicing.
Nucleic Acids Res. 2008 Feb;36(3):814-25. doi: 10.1093/nar/gkm1098. Epub 2007 Dec 15.
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Proximity of conserved U6 and U2 snRNA elements to the 5' splice site region in activated spliceosomes.
EMBO J. 2006 Jun 7;25(11):2475-86. doi: 10.1038/sj.emboj.7601134. Epub 2006 May 11.
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Prp8 protein: at the heart of the spliceosome.
RNA. 2005 May;11(5):533-57. doi: 10.1261/rna.2220705.
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Mutations in U5 snRNA loop 1 influence the splicing of different genes in vivo.
Nucleic Acids Res. 2002 Dec 15;30(24):5476-84. doi: 10.1093/nar/gkf692.

本文引用的文献

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Crystal structure of a model branchpoint-U2 snRNA duplex containing bulged adenosines.
RNA. 2001 May;7(5):682-91. doi: 10.1017/s1355838201002187.
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The question remains: is the spliceosome a ribozyme?
Nat Struct Biol. 2000 Oct;7(10):850-4. doi: 10.1038/79598.
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The complete atomic structure of the large ribosomal subunit at 2.4 A resolution.
Science. 2000 Aug 11;289(5481):905-20. doi: 10.1126/science.289.5481.905.
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Relationship between internucleotide linkage geometry and the stability of RNA.
RNA. 1999 Oct;5(10):1308-25. doi: 10.1017/s1355838299990891.

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