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男孩特发性尿道出血的自然病史。

The natural history of idiopathic urethrorrhagia in boys.

作者信息

Walker B R, Ellison E D, Snow B W, Cartwright P C

机构信息

Division of Urology, University of Utah School of Medicine, Salt Lake City, Utah, USA.

出版信息

J Urol. 2001 Jul;166(1):231-2.

Abstract

PURPOSE

We describe the presenting symptoms, evaluation and natural history of urethrorrhagia in boys.

MATERIALS AND METHODS

The records of 27 consecutive toilet trained boys with idiopathic urethrorrhagia were retrospectively reviewed for information regarding age, symptoms, symptom duration, physical examination, and radiographic, endoscopic and laboratory data. Patient interviews were performed, and the resolution rate, symptom duration and associated urological abnormalities were evaluated.

RESULTS

Mean age at presentation was 10.1 years. Symptoms included urethrorrhagia in 100% and dysuria in 29.6% of cases. Radiographic and laboratory evaluations were normal in all patients except for microscopic hematuria in 57%. Cystourethroscopy in 4 patients revealed bulbar urethral inflammation without stricture in 2. A total of 24 patients (89%) were followed an average of 37 months (range 10 to 106). Complete resolution developed in 46% of cases at 6 months, in 71% at 1 year and in 91.7% overall. The average duration of symptoms was 9.9 months (range 2 weeks to 38 months). In 2 boys (8.3%) urethrorrhagia persisted for 22 and 28 months, and in 1 cystoscopy revealed urethral stricture. Self-limiting urethrorrhagia recurred in 2 patients (8.3%) after initial resolution. Treatment consisted of watchful waiting in all patients except 1 with urethral stricture, who underwent urethral dilation. After urethrorrhagia resolved epididymo-orchitis recurred in 1 case.

CONCLUSIONS

Routine radiographic, laboratory and endoscopic evaluation is unnecessary for evaluating urethrorrhagia. Watchful waiting is indicated because the condition resolves in 71% and 91.7% of patients at 1 and 2 years, respectively. Evaluation should be considered in patients with prolonged urethrorrhagia because urethral stricture may be identified.

摘要

目的

我们描述男孩尿道出血的临床表现、评估及自然病程。

材料与方法

回顾性分析27例连续接受如厕训练的特发性尿道出血男孩的记录,以获取有关年龄、症状、症状持续时间、体格检查以及影像学、内镜和实验室检查数据的信息。进行患者访谈,并评估缓解率、症状持续时间及相关泌尿系统异常情况。

结果

就诊时的平均年龄为10.1岁。症状包括100%的患者有尿道出血,29.6%的患者有尿痛。除57%的患者有镜下血尿外,所有患者的影像学和实验室检查均正常。4例患者行膀胱尿道镜检查,2例显示球部尿道炎症但无狭窄。共有24例患者(89%)接受了平均37个月(范围10至106个月)的随访。6个月时46%的病例完全缓解,1年时71%的病例完全缓解,总体缓解率为91.7%。症状的平均持续时间为9.9个月(范围2周至38个月)。2例男孩(8.3%)尿道出血持续了22个月和28个月,1例膀胱尿道镜检查显示尿道狭窄。2例患者(8.3%)在初始缓解后出现自限性尿道出血复发。除1例尿道狭窄患者接受尿道扩张治疗外,所有患者均采取观察等待。尿道出血缓解后,1例患者复发附睾炎。

结论

评估尿道出血无需常规进行影像学、实验室及内镜检查。建议采取观察等待,因为该疾病在1年和2年时分别有71%和91.7%的患者病情缓解。对于尿道出血持续时间较长的患者应考虑进行评估,因为可能发现尿道狭窄。

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