一名获得性免疫缺陷综合征（艾滋病）合并中性粒细胞减少症患者的鼻眶毛霉菌病。
Rhino-orbital mucormycosis in a patient with acquired immunodeficiency syndrome (AIDS) and neutropenia.
作者信息
Hejny C, Kerrison J B, Newman N J, Stone C M
机构信息
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.
出版信息
Am J Ophthalmol. 2001 Jul;132(1):111-2. doi: 10.1016/s0002-9394(00)00933-8.
PURPOSE
To present a case of rhino-orbital mucormycosis in a patient with AIDS and neutropenia managed without exenteration.
METHODS
Case report.
RESULTS
A 60-year-old African-American man with AIDS developed neutropenia that was probably secondary to antiretroviral therapy. He developed right rhino-orbital mucormycosis and was treated with right partial ethmoidectomy with debridement and liposomal amphotericin B. The infection was cured without need for orbital exenteration, although visual acuity in his right eye ultimately was no light perception.
CONCLUSION
Rhino-orbital mucormycosis is uncommon in patients with AIDS. When rhino-orbital mucormycosis occurs, patients require a careful search for an underlying metabolic derangement such as neutropenia. Treatment should be aggressive, but these patients may not require orbital exenteration.
目的
介绍1例患艾滋病且有中性粒细胞减少症的患者，在未行眶内容摘除术的情况下成功治疗鼻眶毛霉菌病的病例。
方法
病例报告。
结果
一名60岁患艾滋病的非裔美国男性出现中性粒细胞减少症，可能继发于抗逆转录病毒治疗。他患上了右鼻眶毛霉菌病，接受了右侧部分筛窦切除术加清创术及脂质体两性霉素B治疗。感染得以治愈，无需行眶内容摘除术，尽管其右眼最终视力丧失至无光感。
结论
鼻眶毛霉菌病在艾滋病患者中并不常见。当发生鼻眶毛霉菌病时，患者需要仔细排查潜在的代谢紊乱，如中性粒细胞减少症。治疗应积极，但这些患者可能不需要行眶内容摘除术。
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