Poduri K R, Schnitzer E M
Department of Physical Medicine and Rehabilitation, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.
Arch Phys Med Rehabil. 2001 Jul;82(7):996-9. doi: 10.1053/apmr.2001.21866.
Neurogenic bowel in spinal cord injury (SCI) can present with constipation and diarrhea as ongoing problems. Usually, these manifestations are adequately controlled with modification in the bowel program. When these symptoms persist, other causes should be considered. This case report describes a jejunal carcinoid tumor with colonic extension that was diagnosed in a paraplegic patient with persistent constipation and diarrhea. A 39-year-old man sustained a T1 paraplegia with neurogenic bowel and bladder dysfunction from a gunshot wound. His bowels were initially managed adequately with digital disimpaction. Over the next 8 years, he had intermittent constipation that was managed with the addition of various suppositories. He then developed progressively worsening constipation, and other gastrointestinal (GI) symptoms. Although his symptoms initially resolved with medical management, the constipation worsened. Upper endoscopy revealed a submucosal bulge in the duodenal bulb. A month later, gallstones were found on renal ultrasound performed to evaluate recurrent urinary tract infections. He underwent cholecystectomy, but his GI symptoms persisted over the next several months. Repeat upper endoscopy subsequently revealed an ulcerated tumor at the duodenojejunal flexure. An upper-GI scan with small bowel follow through showed a proximal jejunal mass. The patient underwent laparotomy with resection of the mass. Final pathologic diagnosis was malignant carcinoid tumor. This case shows the importance of entertaining other clinical entities in patients with SCI when constipation and diarrhea persist despite adequate management.
脊髓损伤(SCI)所致神经源性肠病可表现为便秘和腹泻等持续性问题。通常,通过调整肠道护理方案,这些症状可得到充分控制。当这些症状持续存在时,应考虑其他病因。本病例报告描述了一名截瘫患者,患有空肠类癌肿瘤并累及结肠,该患者存在持续性便秘和腹泻。一名39岁男性因枪伤导致T1节段截瘫,伴有神经源性肠和膀胱功能障碍。其肠道最初通过手指抠便法得到了充分处理。在接下来的8年里,他间歇性便秘,通过添加各种栓剂进行处理。随后,他的便秘逐渐加重,并出现了其他胃肠道(GI)症状。尽管最初通过药物治疗症状有所缓解,但便秘仍持续恶化。上消化道内镜检查显示十二指肠球部有一个黏膜下隆起。一个月后,为评估复发性尿路感染而进行的肾脏超声检查发现了胆结石。他接受了胆囊切除术,但在接下来的几个月里,其胃肠道症状仍持续存在。随后重复上消化道内镜检查发现十二指肠空肠曲处有一个溃疡型肿瘤。上消化道造影小肠造影显示空肠近端有一个肿块。患者接受了剖腹手术并切除了肿块。最终病理诊断为恶性类癌肿瘤。本病例表明,对于脊髓损伤患者,当尽管进行了充分管理但便秘和腹泻仍持续存在时,考虑其他临床疾病的重要性。