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Controlled release of insulin from injectable biodegradable triblock copolymer.

作者信息

Kim Y J, Choi S, Koh J J, Lee M, Ko K S, Kim S W

机构信息

Center for Controlled Chemical Delivery, University of Utah, Salt Lake City 84112-5820, USA.

出版信息

Pharm Res. 2001 Apr;18(4):548-50. doi: 10.1023/a:1011074915438.

DOI:10.1023/a:1011074915438

PMID:11451045

Abstract

摘要

相似文献

Controlled release of insulin from injectable biodegradable triblock copolymer.

Pharm Res. 2001 Apr;18(4):548-50. doi: 10.1023/a:1011074915438.

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Controlled release of insulin from pH/temperature-sensitive injectable pentablock copolymer hydrogel.

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In vitro and in vivo evaluation of a once-weekly formulation of an antidiabetic peptide drug exenatide in an injectable thermogel.

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本文引用的文献

Intranasal insulin delivery and therapy.

Adv Drug Deliv Rev. 1999 Feb 1;35(2-3):199-234. doi: 10.1016/s0169-409x(98)00073-8.

In situ gelation of PEG-PLGA-PEG triblock copolymer aqueous solutions and degradation thereof.

J Biomed Mater Res. 2000 May;50(2):171-7. doi: 10.1002/(sici)1097-4636(200005)50:2<171::aid-jbm11>3.0.co;2-f.

Drug release from biodegradable injectable thermosensitive hydrogel of PEG-PLGA-PEG triblock copolymers.

J Control Release. 2000 Jan 3;63(1-2):155-63. doi: 10.1016/s0168-3659(99)00194-7.

Biodegradable block copolymers as injectable drug-delivery systems.

Nature. 1997 Aug 28;388(6645):860-2. doi: 10.1038/42218.

In vivo biocompatibility study of ABA triblock copolymers consisting of poly(L-lactic-co-glycolic acid) A blocks attached to central poly(oxyethylene) B blocks.

J Biomed Mater Res. 1996 Jan;30(1):31-40. doi: 10.1002/(SICI)1097-4636(199601)30:1<31::AID-JBM5>3.0.CO;2-S.

Controlled delivery systems for proteins based on poly(lactic/glycolic acid) microspheres.

Pharm Res. 1991 Jun;8(6):713-20. doi: 10.1023/a:1015841715384.

Biological activity of urease formulated in poloxamer 407 after intraperitoneal injection in the rat.

J Pharm Sci. 1992 Jul;81(7):626-30. doi: 10.1002/jps.2600810707.

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Controlled release of insulin from injectable biodegradable triblock copolymer.

作者信息

Kim Y J, Choi S, Koh J J, Lee M, Ko K S, Kim S W

机构信息

Center for Controlled Chemical Delivery, University of Utah, Salt Lake City 84112-5820, USA.

出版信息

Pharm Res. 2001 Apr;18(4):548-50. doi: 10.1023/a:1011074915438.

DOI:10.1023/a:1011074915438

PMID:11451045

Abstract

摘要

相似文献

Controlled release of insulin from injectable biodegradable triblock copolymer.

Pharm Res. 2001 Apr;18(4):548-50. doi: 10.1023/a:1011074915438.

Controlled release of insulin from injectable biodegradable triblock copolymer depot in ZDF rats.

Pharm Res. 2003 Dec;20(12):2008-10. doi: 10.1023/b:pham.0000008050.99985.5c.

Enteric-coated capsules filled with mono-disperse micro-particles containing PLGA-lipid-PEG nanoparticles for oral delivery of insulin.

Int J Pharm. 2015 Apr 30;484(1-2):181-91. doi: 10.1016/j.ijpharm.2015.02.055. Epub 2015 Feb 24.

Controlled release of insulin from pH/temperature-sensitive injectable pentablock copolymer hydrogel.

J Control Release. 2009 Jul 1;137(1):20-4. doi: 10.1016/j.jconrel.2009.02.021. Epub 2009 Mar 12.

Triblock copolymers: synthesis, characterization, and delivery of a model protein.

Int J Pharm. 2005 Jan 20;288(2):207-18. doi: 10.1016/j.ijpharm.2004.09.026. Epub 2004 Nov 30.

Biodegradable triblock copolymer of PLGA-PEG-PLGA enhances gene transfection efficiency.

Pharm Res. 2004 Jan;21(1):50-4. doi: 10.1023/b:pham.0000012151.05441.bf.

A thermo-responsive and self-healing liposome-in-hydrogel system as an antitubercular drug carrier for localized bone tuberculosis therapy.

Int J Pharm. 2019 Mar 10;558:101-109. doi: 10.1016/j.ijpharm.2018.12.083. Epub 2019 Jan 8.

Development of a non-toxic and non-denaturing formulation process for encapsulation of SDF-1α into PLGA/PEG-PLGA nanoparticles to achieve sustained release.

Eur J Pharm Biopharm. 2018 Apr;125:38-50. doi: 10.1016/j.ejpb.2017.12.020. Epub 2018 Jan 8.

In vitro and in vivo evaluation of a once-weekly formulation of an antidiabetic peptide drug exenatide in an injectable thermogel.

J Pharm Sci. 2013 Nov;102(11):4140-9. doi: 10.1002/jps.23735. Epub 2013 Sep 24.

Control of blood glucose by novel GLP-1 delivery using biodegradable triblock copolymer of PLGA-PEG-PLGA in type 2 diabetic rats.

Pharm Res. 2004 May;21(5):827-31. doi: 10.1023/b:pham.0000026435.27086.94.

引用本文的文献

J Anesth. 2025 Jun;39(3):435-444. doi: 10.1007/s00540-025-03485-y. Epub 2025 Apr 5.

Int J Mol Sci. 2023 Jun 5;24(11):9751. doi: 10.3390/ijms24119751.

Pharmacokinetics of Intramuscularly Administered Thermoresponsive Polymers.

Adv Healthc Mater. 2022 Nov;11(22):e2201344. doi: 10.1002/adhm.202201344. Epub 2022 Nov 7.

PCL-PEG copolymer based injectable thermosensitive hydrogels.

J Control Release. 2022 Mar;343:217-236. doi: 10.1016/j.jconrel.2022.01.035. Epub 2022 Jan 25.

Practical strategy to construct anti-osteosarcoma bone substitutes by loading cisplatin into 3D-printed titanium alloy implants using a thermosensitive hydrogel.

Bioact Mater. 2021 May 14;6(12):4542-4557. doi: 10.1016/j.bioactmat.2021.05.007. eCollection 2021 Dec.

Supramolecular Hydrogels for Protein Delivery in Tissue Engineering.

Molecules. 2021 Feb 7;26(4):873. doi: 10.3390/molecules26040873.

Deimmunization of protein therapeutics - Recent advances in experimental and computational epitope prediction and deletion.

Comput Struct Biotechnol J. 2020 Dec 29;19:315-329. doi: 10.1016/j.csbj.2020.12.024. eCollection 2021.

Self-Assemblable Polymer Smart-Blocks for Temperature-Induced Injectable Hydrogel in Biomedical Applications.

Front Chem. 2020 Jan 31;8:19. doi: 10.3389/fchem.2020.00019. eCollection 2020.

Interleukin-15 (dys)regulation of lymphoid homeostasis: Implications for therapy of autoimmunity and cancer.

J Exp Med. 2020 Jan 6;217(1). doi: 10.1084/jem.20191062.

Biodegradable Thermosensitive PLGA-PEG-PLGA Polymer for Non-irritating and Sustained Ophthalmic Drug Delivery.

AAPS J. 2019 Apr 24;21(4):59. doi: 10.1208/s12248-019-0326-x.

本文引用的文献

Intranasal insulin delivery and therapy.

Adv Drug Deliv Rev. 1999 Feb 1;35(2-3):199-234. doi: 10.1016/s0169-409x(98)00073-8.

In situ gelation of PEG-PLGA-PEG triblock copolymer aqueous solutions and degradation thereof.

J Biomed Mater Res. 2000 May;50(2):171-7. doi: 10.1002/(sici)1097-4636(200005)50:2<171::aid-jbm11>3.0.co;2-f.

Drug release from biodegradable injectable thermosensitive hydrogel of PEG-PLGA-PEG triblock copolymers.

J Control Release. 2000 Jan 3;63(1-2):155-63. doi: 10.1016/s0168-3659(99)00194-7.

Biodegradable block copolymers as injectable drug-delivery systems.

Nature. 1997 Aug 28;388(6645):860-2. doi: 10.1038/42218.

In vivo biocompatibility study of ABA triblock copolymers consisting of poly(L-lactic-co-glycolic acid) A blocks attached to central poly(oxyethylene) B blocks.

J Biomed Mater Res. 1996 Jan;30(1):31-40. doi: 10.1002/(SICI)1097-4636(199601)30:1<31::AID-JBM5>3.0.CO;2-S.

Controlled delivery systems for proteins based on poly(lactic/glycolic acid) microspheres.

Pharm Res. 1991 Jun;8(6):713-20. doi: 10.1023/a:1015841715384.

Biological activity of urease formulated in poloxamer 407 after intraperitoneal injection in the rat.

J Pharm Sci. 1992 Jul;81(7):626-30. doi: 10.1002/jps.2600810707.