Allcock R J, O'Sullivan J J, Corris P A
William Leech Centre for Lung Research, Freeman Hospital, High Heaton, Newcastle upon Tyne, UK.
Arthritis Rheum. 2001 Jul;44(7):1660-2. doi: 10.1002/1529-0131(200107)44:7<1660::AID-ART289>3.0.CO;2-W.
The onset of pulmonary hypertension in patients with systemic sclerosis carries a poor prognosis. Atrial septostomy has been used successfully to palliate endstage primary pulmonary hypertension but has not been attempted in other forms of pulmonary vascular disease. We report substantial clinical improvement following atrial septostomy in a patient with systemic sclerosis complicated by severe, isolated pulmonary hypertension. After the procedure, exercise capacity was improved and exertional syncope abolished. We suggest that this procedure should be considered for other patients with this diagnosis.
系统性硬化症患者发生肺动脉高压预后较差。房间隔造口术已成功用于缓解终末期原发性肺动脉高压，但尚未在其他形式的肺血管疾病中尝试过。我们报告了1例患有系统性硬化症并伴有严重孤立性肺动脉高压的患者在接受房间隔造口术后有显著的临床改善。术后，运动能力得到改善，劳力性晕厥消失。我们建议，对于其他患有该诊断的患者应考虑采用此手术。
