同卵双胞胎中的长时间热性惊厥和内侧颞叶癫痫

Prolonged febrile convulsions and mesial temporal lobe epilepsy in an identical twin.

作者信息

Schulz R, Ebner A

机构信息

Klinik Mara, Epilepsiezentrum Bethel, Bielefeld, Germany.

出版信息

Neurology. 2001 Jul 24;57(2):318-20. doi: 10.1212/wnl.57.2.318.

DOI:10.1212/wnl.57.2.318

PMID:11468319

Abstract

The authors report a 30-year-old identical twin who had prolonged febrile convulsions (FC) at the age of 8 months, left mesial temporal lobe epilepsy beginning at the age of 2 years, and left mesial temporal lobe sclerosis (MTS). The unaffected twin had short FC and meningitis at the age of 4 years but remained seizure free. Thus, prolonged FC in children younger than 4 years may precipitate later development of MTS.

摘要

作者报告了一名30岁的同卵双胞胎，其在8个月大时出现长时间热性惊厥（FC），2岁时开始出现左侧颞叶内侧癫痫，以及左侧颞叶内侧硬化（MTS）。未受影响的双胞胎在4岁时出现短暂热性惊厥和脑膜炎，但此后一直无癫痫发作。因此，4岁以下儿童的长时间热性惊厥可能会促使后期发生颞叶内侧硬化。