Germain M A, Dubousset J, Mascard E, Kalifa C
Département de Chirurgie Cervico-Faciale, Institut Gustave-Roussy, 39 rue Camille Desmoulins-94805 Villejuif.
Bull Acad Natl Med. 2000;184(8):1671-84; discussion 1685-6.
Limb salvage surgery is the standard care for most malignant tumor affecting the extremities in the child, and a vascularized fibula transfer is probably the most popular microsurgical option to reconstruct long-bone defects. Between 1994 and 1999, nine children with intractable diseases of the upper limb were treated using free vascularized fibula grafts (one patient had resection in 1983 and initially prosthetic reconstruction, then fibula transplant in 1996). There were 6 boys and 3 girls. Mean age was 10 years (between 6 and 16). Eight patients had defects after sarcoma resection, one had an aggressive enchondroma. The reconstructed sites were the humerus (= 6), the radius (n = 3). The length of the bone defect ranged from 8 to 19 cm (mean: 14.4 cm). The fibula head with the cartilage and the growth plate was used in 3 children. One girl, 4.5 years old with congenital pseudoarthrosis of radius and cubitus had a resection and reconstruction with a U shaped fibula transplant. One patient died from lung and brain metastasis, two years after the reconstruction. There were no local recurrences. The complications were numerous but usually benign; fracture of the grafted fibula n = 7, necessity of additional bone grafts (n = 4) malunion (n = 1) needed reoperation, pseudoarthrosis (n = 2) with reoperation, ankle valgus (n = 1) required reoperation, necrosis of the fibula head (n = 1), radial inclination (n = 1). The ten patients had bone union. The mean period required to obtain radiographic bone union was 5 months. The functional results of the remaining patients were evaluated according to the scale of ENNEKING. The results ranged from 21 to 30 points. Our results were satisfactory with regard to pain, emotional acceptance, manual dexterity. The vascularized fibula graft is indicated in children with large bone defects, more than 8 cm in the humerus, radius and ulna.
保肢手术是治疗儿童大多数累及四肢的恶性肿瘤的标准治疗方法,带血管蒂腓骨移植可能是重建长骨缺损最常用的显微外科选择。1994年至1999年间,9例上肢难治性疾病患儿接受了游离带血管蒂腓骨移植治疗(1例患者于1983年行切除术,最初进行假体重建,1996年行腓骨移植)。其中男孩6例,女孩3例。平均年龄为10岁(6至16岁)。8例患者在肉瘤切除后出现缺损,1例患有侵袭性内生软骨瘤。重建部位为肱骨(=6例)、桡骨(n=3例)。骨缺损长度为8至19厘米(平均:14.4厘米)。3例儿童使用了带有软骨和生长板的腓骨头。1例4.5岁患有先天性桡骨和尺骨假关节的女孩行U形腓骨移植切除术和重建术。1例患者在重建两年后死于肺和脑转移。无局部复发。并发症众多,但通常为良性;移植腓骨骨折(n=7)、需要额外植骨(n=4)、畸形愈合(n=1)需要再次手术、假关节(n=2)需再次手术、足外翻(n=1)需要再次手术、腓骨头坏死(n=1)、桡骨倾斜(n=1)。10例患者均实现骨愈合。获得影像学骨愈合的平均时间为5个月。其余患者的功能结果根据ENNEKING量表进行评估。结果为21至30分。我们在疼痛、情感接受度、手部灵活性方面的结果令人满意。带血管蒂腓骨移植适用于肱骨、桡骨和尺骨骨缺损大于8厘米的儿童。