Yang M, Shen W, Chen L
Fourth Military Medical University, Xi'an 710038.
Zhonghua Fu Chan Ke Za Zhi. 1999 Oct;34(10):600-2.
To determine the relationship between pregnancy induced hypertension (PIH) and acute disseminated intravascular coagulation (DIC).
26 cases with PIH complicated acute DIC were analyzed retrospectively in five hospitals of Xi'an from 1980 to 1997.
(1) In 26 patients with PIH complicated acute DIC, 7 cases died (26.92%), while 17 neonates died (58.62%) in 29 neonates (3 cases were twin pregnancy). Cesarean section and hysterectomy were performed on 7 cases respectively, including 4 cases underwent both of them. (2) The causative factors of PIH complicated acute DIC included placental abruption (7 cases), amniotic fluid embolism (4 cases), eclamptic seizure (4 cases), surgical injury (7 cases) and bleeding (4 cases). 7 cases induced by placental abruption were all cured, 4 cases induced by amniotic fluid embolism all died.
There are close relationship between PIH and DIC, PIH complicated acute DIC is the major cause of maternal and perinatal mortality, special attention should be paid on preventing DIC for PIH.
确定妊娠高血压综合征(PIH)与急性弥散性血管内凝血(DIC)之间的关系。
回顾性分析1980年至1997年西安五家医院收治的26例PIH并发急性DIC患者的临床资料。
(1)26例PIH并发急性DIC患者中,死亡7例(26.92%);29例新生儿(3例为双胎妊娠)中,死亡17例(58.62%)。剖宫产及子宫切除各7例,其中4例同时行此两种手术。(2)PIH并发急性DIC的病因包括胎盘早剥(7例)、羊水栓塞(4例)、子痫发作(4例)、手术创伤(7例)和出血(4例)。7例胎盘早剥患者均治愈,4例羊水栓塞患者均死亡。
PIH与DIC关系密切,PIH并发急性DIC是孕产妇及围产儿死亡的主要原因,对PIH患者应特别注意预防DIC。