用制熟地黄多糖联合司坦唑醇治疗34例慢性再生障碍性贫血
[Treatment of 34 cases of chronic aplastic anemia using prepared Rehmannia polysaccharide associated with stanozolol].
作者信息
Yuan A, Liu C, Huang X
机构信息
Second Affiliated Hospital of Henan Medical University, Zhengzhou 450003.
出版信息
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1998 Jun;18(6):351-3.
OBJECTIVE
To investigate the effect and side effect of prepared Rehmannia polysaccharide (PRP) associated with stanozolol in treating chronic aplastic anemia (CAA).
METHODS
Thirty-four cases of CAA were treated by PRP liquid associated with stanozolol, course of 3 week treatment, and control group (17 cases of CAA) was treated by stanozolol alone.
RESULTS
Effective rate was 85.3% in treatment group, and that of control group was 58.8%, there was significant difference between them (P < 0.05). Symptom remission of treatment group was earlier than that of control group, symptom scoring between two groups, the difference was highly significant (P < 0.01). Blood cell had a distinct elevation after treatment with PRP associated with stanozolol, and had a significant difference in comparing with pre-treatment in treatment group (P < 0.01). Side effect of PRP was not found during treatment of CAA.
CONCLUSIONS
PRP associated with stanozolol to treat CAA has an additional effect, it can accelerate symptom remission without any additional side effect.
目的
探讨制首乌多糖（PRP）联合司坦唑醇治疗慢性再生障碍性贫血（CAA）的疗效及副作用。
方法
34例CAA患者采用PRP液联合司坦唑醇治疗，疗程3周，对照组（17例CAA患者）仅用司坦唑醇治疗。
结果
治疗组有效率为85.3%，对照组为58.8%，两组差异有统计学意义（P<0.05）。治疗组症状缓解早于对照组，两组症状评分差异有高度统计学意义（P<0.01）。PRP联合司坦唑醇治疗后血细胞有明显升高，治疗组与治疗前比较差异有统计学意义（P<0.01）。CAA治疗期间未发现PRP的副作用。
结论
PRP联合司坦唑醇治疗CAA有增效作用，能加速症状缓解且无额外副作用。
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