Lawrence J M, Reckless J P
Diabetes and Lipid Research, Royal United Hospital, Bath BA1 3NG.
Hosp Med. 2001 Jul;62(7):411-6. doi: 10.12968/hosp.2001.62.7.1611.
Type 2 diabetes is increasingly common and can be difficult to control. By directly targeting insulin resistance, the thiazolidinediones offer a new mode of treatment. Here, the pharmacology, clinical trial evidence, side-effects and current clinical uses of pioglitazone are reviewed.