Pradat P F, Dupel-Pottier C, Lacomblez L, Salachas F, Meininger V, Lacomblez L, Spelle L, Bonnaud I, Ribeiro M J, Remy P, Samson Y
Fédération de Neurologie Mazarin, Hôpital de la Pitié-Salpétrière, Paris, France.
Mov Disord. 2001 Jul;16(4):762-4. doi: 10.1002/mds.1126.
An C-flumazenil positron emission tomography (PET) study in a patient with pallido-pyramidal disease revealed a marked decrease in benzodiazepine-receptor density in the precentral gyrus cortex and the mesial frontal cortex. We suggest that, in addition to dysfunction of basal ganglia-dependent systems, degeneration of the supplementary motor area could also be involved in the patient's bradykinesia.