Bulava A, Skvarilová M, Marek O, Lukl J
I. interní klinika Fakultní nemocnice, Olomouc.
Vnitr Lek. 2001 Jun;47(6):407-10.
Transient electrocardiographic changes in patients with acute pancreatitis are well known in the literature. Mostly these changes are in the form of T-wave inversion, ST-segment depression, and rarely ST-segment elevation without the presence of coronary artery disease. We report a patient, in whom electrocardiographic changes mimicked acute inferior myocardial infarction with subsequent evolution of Q-waves in the inferior leads and ischaemia in the anterior wall. To the authors' knowledge, this is the first report documenting the evolution of Q-waves on surface ECG in the absence of myocardial necrosis verified by postmortem examination in the patient, who died of cardiorespiratory failure and massive haemoperitoneum as a complication of ongoing acute necrotizing haemorrhagic pancreatitis. The authors also discuss diagnostic and therapeutic options in patients with acute pancreatitis and ECG pattern of acute myocardial infarction. Acute pancreatitis may mimic acute myocardial ischaemia (or infarction) or these two diseases may be present at the same time. In differential diagnosis, selective coronarography might be helpful and it allows also immediate revascularisation. Administration of thrombolytic therapy in such patients is not safe and might end up with fatal consequences.
急性胰腺炎患者的短暂心电图改变在文献中已广为人知。这些改变大多表现为T波倒置、ST段压低,在无冠状动脉疾病的情况下很少出现ST段抬高。我们报告了一名患者,其心电图改变酷似急性下壁心肌梗死,随后下壁导联出现Q波,前壁出现缺血。据作者所知,这是第一份记录在无心肌坏死经尸检证实的情况下,患者体表心电图上Q波演变的报告,该患者死于心肺功能衰竭和大量腹腔积血,这是正在进行的急性坏死性出血性胰腺炎的并发症。作者还讨论了急性胰腺炎患者的诊断和治疗选择以及急性心肌梗死的心电图模式。急性胰腺炎可能酷似急性心肌缺血(或梗死),或者这两种疾病可能同时存在。在鉴别诊断中,选择性冠状动脉造影可能会有帮助,并且它还允许立即进行血管重建。在此类患者中给予溶栓治疗不安全,可能会导致致命后果。