尼日利亚索科托州和赞法拉州麻风病消除运动的治疗结果及影响

Treatment outcome and impact of leprosy elimination campaign in Sokoto and Zamfara states, Nigeria.

作者信息

Ebenso B E, Tureta S M, Udo S O

机构信息

The Leprosy Mission, Minna, Niger State, Nigeria.

出版信息

Lepr Rev. 2001 Jun;72(2):192-8. doi: 10.5935/0305-7518.20010025.

DOI:10.5935/0305-7518.20010025

PMID:11495450

Abstract

A Leprosy Elimination Campaign (LEC) was implemented in 37 districts of Sokoto and Zamfara states, Nigeria from 13 August to 30 November 1998. The campaign utilized intensive community mobilization and training of local health personnel to detect hidden leprosy cases. During 8 weeks of case finding, 160,127 persons were screened; 353 new cases of leprosy were detected and placed on MDT; 236 (67%) of new cases detected were classified as MB, 64 cases (18%) suffered visible deformities and 24 patients (6.8%) were children. Follow-up in December 1999 of patients placed on MDT revealed 97% PB and 96% MB cure rates, respectively. Detection of cases in communities led some community leaders to ask for repeat surveys in their communities. Repeat surveys continue to yield new cases. The authors recommend that LECs be maintained for 3 years to accelerate leprosy elimination in the region. The cost effectiveness and impact of LEC in Sokoto-Zamfara are discussed.

摘要

1998年8月13日至11月30日，尼日利亚在索科托州和赞法拉州的37个区开展了麻风病消除运动（LEC）。该运动通过深入的社区动员和对当地卫生人员的培训来发现隐匿的麻风病病例。在为期8周的病例发现期间，共筛查了160,127人；发现353例新麻风病病例并为其提供了联合化疗；新发现病例中236例（67%）被归类为多菌型，64例（18%）有可见畸形，24例患者（6.8%）为儿童。1999年12月对接受联合化疗的患者进行随访，显示少菌型和多菌型的治愈率分别为97%和96%。社区病例的发现促使一些社区领导人要求在其社区进行重复调查。重复调查仍不断发现新病例。作者建议将麻风病消除运动维持3年，以加速该地区的麻风病消除。文中还讨论了索科托 - 赞法拉麻风病消除运动的成本效益和影响。