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上呼吸道感染患儿围手术期不良呼吸事件的危险因素

Risk factors for perioperative adverse respiratory events in children with upper respiratory tract infections.

作者信息

Tait A R, Malviya S, Voepel-Lewis T, Munro H M, Seiwert M, Pandit U A

机构信息

Department of Anesthesiology, University of Michigan Health Systems, Ann Arbor 48109, USA.

出版信息

Anesthesiology. 2001 Aug;95(2):299-306. doi: 10.1097/00000542-200108000-00008.

Abstract

BACKGROUND

Anesthesia for the child who presents for surgery with an upper respiratory infection (URI) presents a challenge for the anesthesiologist. The Current prospective study was designed to determine the incidence of and risk factors for adverse respiratory events in children with URTs undergoing elective surgical procedures.

METHODS

The study population included 1,078 children aged 1 month to 18 yr who presented for an elective surgical procedure. Parents were given a short questionnaire detailing their child's demographics, medical history, and presence of any symptoms of a URT. Data regarding the incidence and severity of perioperative respiratory events were collected prospectively. Adverse respiratory events (any episode of laryngospasm, bronchospasm, breath holding > 15 s, oxygen saturation < 90%, or severe cough) were recorded. In addition, parents were contacted 1 and 7 days after surgery to determine the child's postoperative course.

RESULTS

There were no differences between children with active URIs, recent URIs (within 4 weeks), and asymptomatic children with respect to the incidences of laryngospasm and bronchospasm. However, children with active and recent URIs had significantly more episodes of breath holding, major desaturation (oxygen saturation < 90%) events, and a greater incidence of overall adverse respiratory events than children with no URIs. Independent risk factors for adverse respiratory events in children with active URIs included use of an endotracheal tube (< 5 yr of age), history of prematurity, history of reactive airway disease, paternal smoking, surgery involving the airway, the presence of copious secretions, and nasal congestion. Although children with URIs had a greater incidence of adverse respiratory events, none were associated with any long-term adverse sequelae.

CONCLUSIONS

The current study identified several risk factors for perioperative adverse respiratory events in children with lulls. Although children with acute and recent URIs are at greater risk for respiratory complications, these results suggest that most of these children can undergo elective procedures without significant increase in adverse anesthetic outcomes.

摘要

背景

为患有上呼吸道感染(URI)的儿童实施手术麻醉,对麻醉医生来说是一项挑战。当前的前瞻性研究旨在确定接受择期外科手术的URI患儿发生不良呼吸事件的发生率及危险因素。

方法

研究人群包括1078名年龄在1个月至18岁之间接受择期外科手术的儿童。向家长发放一份简短问卷,详细询问孩子的人口统计学信息、病史以及是否存在任何URI症状。前瞻性收集围手术期呼吸事件的发生率和严重程度数据。记录不良呼吸事件(任何喉痉挛、支气管痉挛、屏气超过15秒、氧饱和度<90%或严重咳嗽发作)。此外,在术后1天和7天与家长联系,了解孩子的术后情况。

结果

活动性URI患儿、近期URI(4周内)患儿与无症状患儿在喉痉挛和支气管痉挛发生率方面无差异。然而,活动性和近期URI患儿的屏气发作、严重低氧血症(氧饱和度<90%)事件明显多于无URI患儿,总体不良呼吸事件发生率也更高。活动性URI患儿发生不良呼吸事件的独立危险因素包括使用气管插管(<5岁)、早产史、反应性气道疾病史、父亲吸烟、气道相关手术、大量分泌物以及鼻塞。尽管URI患儿不良呼吸事件发生率更高,但均未出现任何长期不良后遗症。

结论

本研究确定了URI患儿围手术期不良呼吸事件的若干危险因素。尽管急性和近期URI患儿发生呼吸并发症的风险更高,但这些结果表明,大多数此类患儿可接受择期手术,而不会显著增加不良麻醉结局的发生率。

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