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棋盘水蛇(渔游蛇)中睾酮的代谢效应

Metabolic effects of testosterone in the chequered water-snake, Natrix piscator.

作者信息

Thapliyal J P, Gupta S C, Garg R K

出版信息

J Endocrinol. 1975 Jun;65(3):333-9. doi: 10.1677/joe.0.0650333.

DOI:10.1677/joe.0.0650333
PMID:1151231
Abstract

In the water-snake, Natrix piscator, the following are depressed by orchidectomy and restored to normal by testosterone treatment: glucose, free and esterified fatty acids and triglycerides in plasma, hepatic triglycerides, and total esterified fatty acids. The increase in hepatic free fatty acids and muscle glycogen was also reduced to the level found in intact snakes. Moreover, although castration had no effect, testosterone caused a significant increase in liver weight and plasma protein, and a significant decrease in free plasma cholesterol. Except for an increase in triglyceride content by high doses of the hormone, neither castration nor the administration of 5 mg testosterone had any significant effect on the free fatty acid and triglyceride content of the adipose tissue of the snakes.

摘要

在水蛇渔游蛇(Natrix piscator)中,以下指标经睾丸切除后降低,并通过睾酮治疗恢复正常:血浆中的葡萄糖、游离脂肪酸和酯化脂肪酸以及甘油三酯、肝脏甘油三酯和总酯化脂肪酸。肝脏游离脂肪酸和肌肉糖原的增加也降至完整蛇类中的水平。此外,虽然去势没有影响,但睾酮使肝脏重量和血浆蛋白显著增加,血浆游离胆固醇显著降低。除了高剂量激素使甘油三酯含量增加外,去势和注射5毫克睾酮对蛇类脂肪组织的游离脂肪酸和甘油三酯含量均无显著影响。

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1
Metabolic effects of testosterone in the chequered water-snake, Natrix piscator.棋盘水蛇(渔游蛇)中睾酮的代谢效应
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