Arora N, Daga M K, Mahajan R, Prakash S K, Gupta N
Department of Medicine, Maulana Azad Medical College and Associated Hospitals, New Delhi.
Indian J Chest Dis Allied Sci. 2001 Jul-Sep;43(3):157-62.
Chronic bronchitis is associated with acute exacerbation, most often infective in origin. In order to study the bacteriological profile in such cases a total of 58 patients were enrolled in this study from the chest clinic of our hospital. The male to female ratio was 2 to 1. Mean age of study group was 47 years. All patients had increased cough and sputum production. Barlett count, gram stain and sputum cultures were done for all patients. IgM and IgG antibodies for M. pneumoniae by ELISA were estimated in all cases. The etiological diagnosis could be established in 72% cases. S. pneumoniae (25.8%), P. aeruginosa (12%), Klebsiella sp (10.3%), B. catarrhalis (3.4%), S. aureus (1.7%) were isolated. Although M. pneumoniae was not cultured it was demonstrated serologically in 20% of cases. H. influenzae was not isolated in any case. The frequency of isolating an etiological agent increased with severity of dysponea.
慢性支气管炎常伴有急性加重，其病因大多为感染性。为研究此类病例的细菌学特征，我们从我院胸科门诊纳入了58例患者进行本研究。男女比例为2:1。研究组的平均年龄为47岁。所有患者均有咳嗽加剧和痰液增多的症状。对所有患者进行了巴氏计数、革兰氏染色和痰培养。所有病例均通过酶联免疫吸附测定法检测了肺炎支原体的IgM和IgG抗体。72%的病例可明确病因诊断。分离出的病原菌有肺炎链球菌（25.8%）、铜绿假单胞菌（12%）、克雷伯菌属（10.3%）、卡他莫拉菌（3.4%）、金黄色葡萄球菌（1.7%）。虽然未培养出肺炎支原体，但20%的病例通过血清学检测得到证实。未分离出任何1例流感嗜血杆菌。分离出病原体的频率随呼吸困难的严重程度增加而升高。
