Murthy S, Hawksworth N
Royal Glamorgan Hospital, Llantrisant CF 72 8 XR, United Kingdom.
Am J Ophthalmol. 2001 Sep;132(3):410-1. doi: 10.1016/s0002-9394(01)00998-9.
Pigmentary glaucoma is a bilateral disorder. When it occurs asymmetrically or unilaterally, a cause should be sought because it may help us to understand the pathophysiology of this condition better. We describe a patient with unilateral pigmentary glaucoma and the Adie pupil in the same eye and discuss the possible role of the Adie pupil in the development of the pigmentary glaucoma.
A case report. A 37-year-old woman presented with asymmetric pigment dispersion resulting in pigmentary glaucoma in the right eye and an unilateral Adie pupil in the same eye.
We believe that the dilated Adie pupil in the right eye might have resulted in a decreased amount of relative pupillary block. This, then, might have led to an increased contact between the posterior iris and the zonules, resulting in greater pigment dispersion and trabecular obstruction in the right eye.
It has been proposed that the pigment is liberated from the iris pigment epithelium because of the mechanical rubbing of the posterior iris against the anterior zonular packets. Our case supports this proposed mechanism of pigment release.
色素性青光眼是一种双侧性疾病。当它不对称或单侧发生时,应寻找病因,因为这可能有助于我们更好地理解这种疾病的病理生理学。我们描述了一位患有单眼色素性青光眼且同一眼伴有阿-罗瞳孔的患者,并讨论了阿-罗瞳孔在色素性青光眼发病过程中的可能作用。
病例报告。一名37岁女性,表现为不对称性色素播散,导致右眼色素性青光眼,且同一眼有单侧阿-罗瞳孔。
我们认为右眼扩大的阿-罗瞳孔可能导致相对瞳孔阻滞量减少。进而,这可能导致虹膜后表面与小带之间的接触增加,从而导致右眼色素播散增多和小梁阻塞。
有人提出色素是由于虹膜后表面与前部小带束的机械摩擦而从虹膜色素上皮释放出来的。我们的病例支持这种色素释放的假说机制。