Nucleic acid analogues and the origins of replication.
作者信息
Schwartz A W
机构信息
Laboratory for Exobiology, University of Nijmegen, The Netherlands.
出版信息
Adv Space Res. 1989;9(6):77-81. doi: 10.1016/0273-1177(89)90211-1.
PMID:11537377
Abstract
Recent interest in the properties of "nucleic acid-like structures" has been stimulated by difficulties encountered in the synthesis and nonenzymatic oligomerization of nucleotides. However, none of the newly proposed monomers has yet been synthesized in a plausibly prebiotic manner. Arguments are presented that analogues based on 8-hydroxymethyladenine and 5-hydroxymethyluracil are promising candidates for primitive nucleotide precursors.
摘要
相似文献
1
Nucleic acid analogues and the origins of replication.
Adv Space Res. 1989;9(6):77-81. doi: 10.1016/0273-1177(89)90211-1.
2
Was adenine the first purine?
Science. 1989 Sep 8;245:1102-4. doi: 10.1126/science.11538344.
3
Prebiotic synthesis of 5-substituted uracils: a bridge between the RNA world and the DNA-protein world.
Science. 1995 May 5;268(5211):702-5. doi: 10.1126/science.7732378.
4
Prebiotic synthesis of adenine and amino acids under Europa-like conditions.
Icarus. 2000 Jun;145(2):609-13. doi: 10.1006/icar.2000.6365.
5
Prebiotic syntheses of purines and pyrimidines.
Adv Space Res. 1984;4(12):125-31. doi: 10.1016/0273-1177(84)90554-4.
6
An investigation of prebiotic purine synthesis from the hydrolysis of HCN polymers.
Orig Life Evol Biosph. 2005 Apr;35(2):79-90. doi: 10.1007/s11084-005-5945-9.
7
The prebiotic role of adenine: a critical analysis.
Orig Life Evol Biosph. 1995 Jun;25(1-3):83-98. doi: 10.1007/BF01581575.
8
The prebiotic synthesis of modified purines and their potential role in the RNA world.
J Mol Evol. 1999 Jun;48(6):631-7. doi: 10.1007/pl00006506.
9
The gamma-irradiation of aqueous hydrogen cyanide in the presence of ferrocyanide or ferricyanide: implications to prebiotic chemistry.
Adv Space Res. 1989;9(6):57-61. doi: 10.1016/0273-1177(89)90208-1.
10
Synthesis of long prebiotic oligomers on mineral surfaces.
Nature. 1996 May 2;381(6577):59-61. doi: 10.1038/381059a0.
Zotero 插件