Sobel B E
Adv Cardiol. 1975;15:86-98. doi: 10.1159/000397667.
Quantitative assessment of infarct size is becoming increasingly important, particularly since this parameter appears to be a major determinant of prognosis. Morphologic, radioisotopic and electrophysiological techniques for assessing the extent of irreversible ischemic injury entail certain unavoidable limitations. Experimental and preliminary clinical findings suggest that estimation of the extent of infarction from biochemical markers in serum is practical and useful. Furthermore, prediction of infarct size during its early evolution may improve selection of patients for interventions designed to protect ischemic myocardium and may contribute to objective assessment of their efficacy.
梗死面积的定量评估正变得越来越重要，特别是因为该参数似乎是预后的主要决定因素。用于评估不可逆性缺血损伤程度的形态学、放射性同位素和电生理技术存在某些不可避免的局限性。实验和初步临床研究结果表明，根据血清中的生化标志物来估计梗死范围是可行且有用的。此外，在梗死早期演变过程中预测梗死面积，可能会改善对旨在保护缺血心肌的干预措施的患者选择，并有助于对其疗效进行客观评估。
