Vagts D A, Nöldge-Schomburg G F
Klinik und Poliklinik für Anästhesiologie und Intensivtherapie, Universität Rostock.
Anaesthesiol Reanim. 2001;26(4):96-101.
Over the last 20 years there has been increasing interest in the pivotal role of the splanchnic region in the development of SIRS, sepsis and multiple organ failure. One key question is how to monitor and detect in good time regional splanchnic perfusion, oxygenation and impaired function of liver and gut, so as to start appropriate therapeutic measures. This review describes the pathophysiological background of impaired splanchnic perfusion. It focuses on the advantages and risks of methods of monitoring splanchnic perfusion or oxygenation and considers them regarding clinical relevance and usefulness. Special emphasis is laid on gastric tonometry. Despite all the restrictions and the criticism which can be levelled at this method, it remains the only way of monitoring splanchnic perfusion and oxygenation that is currently applicable in clinical routine. The data gained can be useful if clinicians are aware of the weak points of tonometry and consider the data in the overall clinical picture. When this is done, the patient can profit from gastric tonometry and the benefits outweigh the risks.
在过去20年里,人们对内脏区域在全身炎症反应综合征(SIRS)、脓毒症和多器官功能衰竭发展过程中的关键作用越来越感兴趣。一个关键问题是如何及时监测和检测内脏区域的灌注、氧合以及肝脏和肠道功能受损情况,以便启动适当的治疗措施。这篇综述描述了内脏灌注受损的病理生理背景。它重点关注监测内脏灌注或氧合方法的优缺点,并从临床相关性和实用性方面进行考量。特别强调了胃张力测定法。尽管这种方法存在诸多限制和受到一些批评,但它仍然是目前临床常规中唯一可用于监测内脏灌注和氧合的方法。如果临床医生了解张力测定法的弱点并将这些数据纳入整体临床情况进行考虑,那么所获得的数据可能会很有用。这样做时,患者可以从胃张力测定法中获益,且益处大于风险。