Hoflack L, Yeung M K
Department of Pediatric Dentistry, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Oral Microbiol Immunol. 2001 Oct;16(5):319-20. doi: 10.1034/j.1399-302x.2001.016005319.x.
The nucleotide sequence of the chromosomal DNA, upstream of Actinomyces naeslundii T14V fimbrial gene fimA, was determined. One open reading frame (orf977) encoding 977 amino acids was found, preceded by a gene homologous to elongation factor TU. Database searches revealed that Orf977 was homologous to CshA, a Streptococcus gordonii protein involved in cell adhesion. Previous studies had already determined two genes in the type 2 fimbrial gene cluster of A. naeslundii T14V: the structural subunit fimA, and orf365 with unknown function, followed by ribosomal genes. This study completes the type 2 fimbrial gene cluster sequence.
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