Bener A, Lestringant G G, Nyomba B L, Frossard P, Saadi H
Department of Community Medicine, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, United Arab Emirates.
East Mediterr Health J. 2000 Mar-May;6(2-3):416-24.
We examined the association between acanthosis nigricans, hyperinsulinaemia and other risk factors for cardiovascular disease in patients from the United Arab Emirates. Height, weight and sitting blood pressure were recorded in 122 patients with acanthosis nigricans, and blood samples were obtained for measuring fasting cholesterol, high-density lipoprotein cholesterol, triglyceride and uric acid levels. In addition, a glucose tolerance test was performed and blood was sampled for insulin and glucose. Our results indicate that the patients with acanthosis nigricans had a high prevalence of abnormal glucose tolerance and hyperinsulinaemia. In addition, euglycaemic patients with hyperinsulinaemia had a cluster of risk factors for cardiovascular disease.
我们研究了阿联酋患者中黑棘皮症、高胰岛素血症与其他心血管疾病危险因素之间的关联。记录了122例黑棘皮症患者的身高、体重和坐位血压，并采集血样以测定空腹胆固醇、高密度脂蛋白胆固醇、甘油三酯和尿酸水平。此外，进行了葡萄糖耐量试验，并采集血样检测胰岛素和葡萄糖。我们的结果表明，黑棘皮症患者糖耐量异常和高胰岛素血症的患病率较高。此外，糖耐量正常的高胰岛素血症患者存在一系列心血管疾病危险因素。
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