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经皮穿刺并使用正丁基氰基丙烯酸酯(NBCA)栓塞治疗下颌骨中心性血管瘤的根治性治疗。

Curative treatment of central hemangioma in the mandible by direct puncture and embolisation with n-butyl-cyanoacrylate (NBCA).

作者信息

Kaneko R, Tohnai I, Ueda M, Negoro M, Yoshida J, Yamada Y

机构信息

Department of Oral and Maxillofacial Surgery, Nagoya University Postgraduate School of Medicine, 65 Tsuruma-cho, Showa-ku, Nagoya 466-8550, Japan.

出版信息

Oral Oncol. 2001 Oct;37(7):605-8. doi: 10.1016/s1368-8375(00)00119-6.

Abstract

Management of central hemangioma in the mandible is difficult because of the abundant vascular network in this region. One of the most common signs of these patients, especially in the mixed dentition period, is hypermobility of the teeth with spontaneous hemorrhage from the surrounding gingival sulcus. Various therapeutic modalities have been considered, but surgery is the most frequently used. In cases of a large extensive lesion, however, intralesional injections of sclerosing agents have often been successful. A case of central hemangioma of the mandible with arteriovenous malformations in a 10-year-old girl is reported. She was treated with direct injection of an embolic material, n-butyl-cyanoacrylate, which brought satisfactory results. Preoperative embolisation of feeder vessels with Gelfoam and Avitene soaked in thrombin together with this direct injection is a safe treatment modality that is as effective as surgery.

摘要

由于下颌骨区域血管网络丰富,下颌骨中央血管瘤的治疗颇具难度。这些患者最常见的症状之一,尤其是在混合牙列期,是牙齿松动并伴有来自周围龈沟的自发性出血。人们考虑过各种治疗方法,但手术是最常用的。然而,对于大面积广泛病变的病例,病灶内注射硬化剂常常取得成功。本文报道了一名10岁女孩下颌骨中央血管瘤伴动静脉畸形的病例。她接受了栓塞材料正丁基氰基丙烯酸酯的直接注射治疗,取得了满意的效果。术前用浸泡过凝血酶的明胶海绵和微纤维胶原止血剂对供血血管进行栓塞,再加上这种直接注射,是一种安全的治疗方式,其效果与手术相当。

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