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[Misleading advertisement of Adalat Oros].

作者信息

Verheugt F W

机构信息

Academisch Ziekenhuis St Radboud, afd. Cardiologie, Postbus 9101, 6500 HB Nijmegen.

出版信息

Ned Tijdschr Geneeskd. 2001 Sep 8;145(36):1751-2.

Abstract

Referring to the INSIGHT trial published in The Lancet, Bayer Netherlands states in an advertisement in Dutch medical journals that nifedipine reduces cardiovascular events by 50% in patients with hypertension and at least one additional risk factor. However, the agent studied in the INSIGHT trial did not reduce cardiovascular events in comparison to treatment with a diuretic. On the contrary, the incidence of myocardial infarction increased (fatal infarction even increased significantly), and the risk of stroke was not significantly reduced. Therefore the advertisement is misleading.

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