Carreiro G, da Luz Moreira A, Murad F F, Azevedo F, Coelho H S
Serviço de Gastroenterologia e Serviço de Radiologia do Departamento de Clínica Médica, Universidade Federal do Rio de Janeiro-UFRJ-Hospital Clementino Fraga Filho, Rio de Janeiro, RJ.
Arq Gastroenterol. 2001 Jan-Mar;38(1):69-80. doi: 10.1590/s0004-28032001000100013.
At the present time several therapeutic options are used for the treatment of bleeding esophageal varices in patients with portal hypertension. We will review the main medical publications on transjugular intrahepatic portosystemic shunt (TIPS), a procedure seldom used among us. TIPS works as a portocaval side-to-side shunt and decreases the risk of esophageal bleeding through lowering of the portal system pressure and a decrease of the portal hepatic pressure gradient. TIPS consists in the percutaneous insertion, through the internal jugular vein, of a metallic stent under fluoroscopic control in the hepatic parenchyma creating a true porta caval communication. There are several studies demonstrating the efficacy of TIPS, although only a few of them are randomized and control-matched to allow us to conclude that this procedure is safe, efficient and with a good cost benefit ratio. In this review, we search for the analysis of the TIPS utilization, its techniques, its major indications and complications. TIPS has been used in cases of gastroesophageal bleeding that has failed with pharmacologic or endoscopic treatment in patients Child-Pugh B and C. It can be used also as a bridge for liver transplantation. Others indications for TIPS are uncontrolled ascites, hepatic renal syndrome, and hepatic hydrothorax. The main early complications of TIPS using are related to the insertion site and hepatic encephalopathy and the stent occlusion is the chief late complication.
目前,有几种治疗方法用于治疗门静脉高压患者的食管静脉曲张出血。我们将回顾关于经颈静脉肝内门体分流术(TIPS)的主要医学出版物,这是一种在我们之中很少使用的手术。TIPS作为一种门腔侧侧分流术,通过降低门静脉系统压力和门静脉肝压力梯度来降低食管出血的风险。TIPS包括在透视控制下经皮通过颈内静脉将金属支架插入肝实质,建立真正的门腔交通。有几项研究证明了TIPS的疗效,尽管其中只有少数是随机且有对照匹配的,以便我们得出该手术安全、有效且成本效益比良好的结论。在本综述中,我们寻求对TIPS的应用、技术、主要适应症和并发症进行分析。TIPS已用于Child-Pugh B级和C级患者经药物或内镜治疗失败的胃食管出血病例。它也可作为肝移植的桥梁。TIPS的其他适应症是难治性腹水、肝肾综合征和肝性胸水。使用TIPS的主要早期并发症与插入部位和肝性脑病有关,支架闭塞是主要的晚期并发症。