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[白塞病:回顾性研究]

[Behcet's disease: retrospective study].

作者信息

Baixauli A, Calvo J, Tamarit J J, Campos C, García S, Herrera A

机构信息

Sección Reumatología y Osteoporosis, Servicio Medicina Interna, Hospital General Universitario, Avda. Tres Cruces, s/n. 46014 Valencia.

出版信息

An Med Interna. 2001 Aug;18(8):405-10.

Abstract

BACKGROUND

Since the criteria for the diagnosis of Behçet's disease was established several isolated cases have been reported to the literature with clinical manifestations associated. We tried to analyze the clinical parameters associated to this disease in 24 patients in our hospital.

METHODS

A retrospective analysis was made of the patients diagnosed of Behçet's disease at Hospital General of Valencia since 1990 to 2000. The diagnosis of Behçet's disease was made by the criteria of the International Study Group for Behçet disease. Data regarding personal, clinical manifestations and clinical course were collected.

RESULTS

Of the 24 cases, fourteen (58%) were men and ten (42%) were women. The median of the diagnosed was 33 years. All of them had oral recidivant ulcers. The genital ulcers appeared in twenty (83%) cases. Thirteen cases (54%) had ocular manifestations, and the skin lesions appear in 10 cases (42%). We review other clinical manifestations associated to Behçet disease: articular clinical appear in 17 cases (70%), digestive manifestations in six cases (25%), neurological manifestations three cases (12%), vascular clinical two cases (8%).

CONCLUSIONS

Our results are similar to the Mediterranean expression of Behçet's disease. We must study the clinical manifestations associated to this disease that are not include in the criteria of diagnosis.

摘要

背景

自从白塞病的诊断标准确立以来,已有数例伴有相关临床表现的孤立病例被报道。我们试图分析我院24例该疾病患者的相关临床参数。

方法

对1990年至2000年在巴伦西亚综合医院被诊断为白塞病的患者进行回顾性分析。白塞病的诊断依据国际白塞病研究组的标准。收集了有关个人情况、临床表现和临床病程的数据。

结果

24例患者中,14例(58%)为男性,10例(42%)为女性。诊断时的年龄中位数为33岁。所有患者均有复发性口腔溃疡。20例(83%)出现生殖器溃疡。13例(54%)有眼部表现,10例(42%)出现皮肤病变。我们回顾了与白塞病相关的其他临床表现:关节表现出现在17例(70%)中,消化系统表现出现在6例(25%)中,神经系统表现出现在3例(12%)中,血管表现出现在2例(8%)中。

结论

我们的结果与白塞病在地中海地区的表现相似。我们必须研究诊断标准中未涵盖的与该疾病相关的临床表现。

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