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[ Gilles de la Tourette综合征:58例临床研究]

[Gilles de la Tourette syndrome: a clinical study on 58 cases].

作者信息

Fen C H, Barbosa E R, Miguel E C

机构信息

Divisão de Clínica Neurológica, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.

出版信息

Arq Neuropsiquiatr. 2001 Sep;59(3-B):729-32. doi: 10.1590/s0004-282x2001000500015.

Abstract

Gilles de la Tourette's syndrome (GTS) is a neuropsychiatric disorder with a childhood onset and is characterized by motor and vocal tics. Fifty-eight patients with GTS were evaluated during a period of three years. Thirty-six patients were male and twenty two female, with an age range of 7 to 51 years (mean 20.33 years). The male to female ratio was 1.6:1. The age of onset ranged from 3 to 15 years (mean 7.81 years). Seventy nine percent of the patients presented motor tics as the initial symptom of the disease. In terms of complex tics, coprolalia was present in 27.6% of the patients; copropraxia in 20.1%; palilalia in 20.1%; ecolalia in 27.6%; and ecopraxia in 27,6%. Associated manifestations, such as attention deficit, hyperactivity disorder and obsessive-compulsive disorder were present in 25.8% and 39.6%, respectively. Sensory phenomena were present in 54.8% of the patients.

摘要

Gilles de la Tourette综合征(GTS)是一种起病于儿童期的神经精神障碍,以运动性和发声性抽动为特征。在三年期间对58例GTS患者进行了评估。其中36例为男性,22例为女性,年龄范围为7至51岁(平均20.33岁)。男女比例为1.6:1。发病年龄范围为3至15岁(平均7.81岁)。79%的患者以运动性抽动作为疾病的首发症状。在复杂性抽动方面,秽语症见于27.6%的患者;模仿动作见于20.1%;重复语言见于20.1%;重复言语见于27.6%;模仿行为见于27.6%。注意缺陷、多动障碍和强迫症等相关表现分别见于25.8%和39.6%的患者。54.8%的患者存在感觉现象。

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