Wang T, Liu L, Li Z, Hu S, Yang W, Zhu X
Department of Ophthalmology, Tongren Hospital, Capital University of Medical Sciences, Beijing 100730, China.
Chin Med J (Engl). 1999 Mar;112(3):217-20.
To observe the changes of the ocular anterior segment structure and the relationship between the intraocular pressure (IOP) and these changes after the topical application of cycloplegia using ultrasound biomicroscope (UBM), especially to observe the changes of ciliary body thickness, ciliary process thickness and ciliary process-lens distance.
The quantitative measurement with UBM and the measurement of IOP were performed before and after the topical application of 2% homatropine solution in 48 normal eyes. The results were statistically analyzed.
In the parameters showing the changes of the anterior chamber angle after topical use of 2% homatropine solution, both the trabecular iris angle and the angle opening distance 250 decreased. The iris thickness 1 increased. The anterior chamber became deeper and the iris-lens contact distance became shorter. All these differences were statistically significant (P < 0.05). In the parameters showing the changes of ciliary body, the ciliary body thickness and the ciliary process thickness decreased. The scleral ciliary body angle increased. The iris-zonule distance decreased and the ciliary process-lens distance increased. All these differences were statistically significant (P < 0.05). The IOP increased from 17.63 +/- 3.45 mm Hg to 18.23 +/- 3.53 mm Hg after topical use of 2% homatropine solution, but the difference was not statistically significant (P > 0.05).
After the topical use of cycloplegia, the anterior chamber becomes deeper. The anterior chamber angle becomes narrower, and the ciliary body becomes thinner and moves backward and the ciliary process-lens distance increases. By using UBM the structures of the ocular anterior segment in the living state can be observed and measured quantitatively. The ultrasound biomicroscopic imaging has its advantages in the morphological study of the ocular anterior segment.
应用超声生物显微镜（UBM）观察局部应用睫状肌麻痹剂后眼前段结构的变化以及眼压（IOP）与这些变化之间的关系，尤其观察睫状体厚度、睫状突厚度及睫状突 - 晶状体距离的变化。
对48只正常眼局部应用2%后马托品溶液前后进行UBM定量测量及眼压测量，并对结果进行统计学分析。
局部应用2%后马托品溶液后，在显示前房角变化的参数中，小梁虹膜角和房角开放距离250均减小，虹膜厚度1增加，前房变深，虹膜 - 晶状体接触距离缩短。所有这些差异均有统计学意义（P < 0.05）。在显示睫状体变化的参数中，睫状体厚度和睫状突厚度减小，巩膜睫状体角增大，虹膜 - 悬韧带距离减小，睫状突 - 晶状体距离增加。所有这些差异均有统计学意义（P < 0.05）。局部应用2%后马托品溶液后眼压从17.63±3.45 mmHg升高至18.23±3.53 mmHg，但差异无统计学意义（P > 0.05）。
局部应用睫状肌麻痹剂后，前房变深，前房角变窄，睫状体变薄并向后移位，睫状突 - 晶状体距离增加。通过UBM可对活体状态下的眼前段结构进行观察和定量测量，超声生物显微镜成像在眼前段形态学研究中具有优势。
