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Expression of pituitary adenylate cyclase-activating polypeptide mRNA in the cochlea of rats.

作者信息

Kawano H, Shimozono M, Tono T, Miyata A, Komune S

机构信息

Department of Otorhinolaryngology, Miyazaki Medical College, 5200 Kihara, Kiyotake-cho, 889-1602, Miyazaki, Japan.

出版信息

Brain Res Mol Brain Res. 2001 Oct 19;94(1-2):200-3. doi: 10.1016/s0169-328x(01)00241-8.

Abstract

Expression of mRNA for pituitary adenylate cyclase-activating polypeptide (PACAP) was detected in the cochlea of rats using a reverse transcription-polymerase chain reaction and in situ hybridization. Examination of in situ hybridization demonstrated that cells in the spiral ganglion, and marginal cells in the stria vascularis expressed mRNA for PACAP. These findings suggest that PACAP may play an important role in regulating cochlear functions.

摘要

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