[党参对犬胃酸、血清胃泌素及血浆生长抑素浓度的影响]

[The effect of Codonopsis pilosula (Franch.) Nannf. on gastric acid, serum gastrin and plasma somatostatin concentration in dogs].

作者信息

Chen S, Zhou Z, Sun S, Li Y, Li X

机构信息

Second Clinical College of China Medical University, Shenyang 110003.

出版信息

Zhongguo Zhong Yao Za Zhi. 1998 May;23(5):299-301, 320.

PMID:11601317

Abstract

The results were obtained by oral administration of the decoction of Codonopsis pilosula in three different doses(10 g, 20 g, 40 g) to 5 dogs with Heidenhain pouch. No significant changes occurred in the acidity output of Heidenhain pouch and plasma somatostatin concentration out of the oral administration (P > 0.05). A significant increase occurred in serum gastrin concentration (P < 0.05 or P < 0.01) 150 min after a dose of 10 g, 90 min and 150 min after doses of 20 g, and 30 min, 60 min, and 150 min after doses of 40 g.

摘要

对5只装有海登海因小胃的狗分别口服三种不同剂量（10克、20克、40克）的党参水煎剂，得到如下结果。口服给药后，海登海因小胃的胃酸分泌量和血浆生长抑素浓度无显著变化（P>0.05）。服用10克剂量后150分钟、20克剂量后90分钟和150分钟、40克剂量后30分钟、60分钟和150分钟，血清胃泌素浓度显著升高（P<0.05或P<0.01）。